靶点信息14(本栏目收费,不能显示细节,电话13136136841)
靶点信息
标题
内容
相关药物
状态
TARGETID
T32137
FORMERID
TTDNC00395
TARGNAME
NADPH oxidase (NOX)
TARGTYPE
Clinical trial target
FUNCTION
NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain.
DRUGINFO
GKT-137831
DRUGINFO
SINOMENINE
KEGGPATH
hsa04066:HIF-1 signaling pathway
KEGGPATH
hsa04145:Phagosome
KEGGPATH
hsa04380:Osteoclast differentiation
KEGGPATH
hsa04670:Leukocyte transendothelial migration
WIKIPATH
WP231:TNF alpha Signaling Pathway
WIKIPATH
WP2877:Vitamin D Receptor Pathway
INTEPATH
rac1_pathway:RAC1 signaling pathway
目标的 KEGG 通路数据
标题内容
hsa04066
hsa04145
hsa04380
hsa04670
目标的 Wiki 路径数据
标题内容
WP2877
WP231
目标的蛋白质ID
标题内容
目标的序列数据
标题内容
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