靶点信息20(本栏目收费,不能显示细节,电话13136136841)
靶点信息
标题
内容
相关药物
状态
TARGETID
T31956
FORMERID
TTDR00531
UNIPROID
AMPE_HUMAN
TARGNAME
Glutamyl aminopeptidase (ENPEP)
GENENAME
ENPEP
TARGTYPE
Clinical trial target
SYNONYMS
ENPEP; EAP; Differentiation antigen gp160; Aminopeptidase A; APA
FUNCTION
Appears to have a role in the catabolicpathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.
PDBSTRUC
4KXD; 4KXC; 4KXB; 4KXA; 4KX9
BIOCLASS
Peptidase
ECNUMBER
EC 3.4.11.7
SEQUENCE
MNFAEREGSKRYCIQTKHVAILCAVVVGVGLIVGLAVGLTRSCDSSGDGGPGTAPAPSHLPSSTASPSGPPAQDQDICPASEDESGQWKNFRLPDFVNPVHYDLHVKPLLEEDTYTGTVSISINLSAPTRYLWLHLRETRITRLPELKRPSGDQVQVRRCFEYKKQEYVVVEAEEELTPSSGDGLYLLTMEFAGWLNGSLVGFYRTTYTENGQVKSIVATDHEPTDARKSFPCFDEPNKKATYTISITHPKEYGALSNMPVAKEESVDDKWTRTTFEKSVPMSTYLVCFAVHQFDSVKRISNSGKPLTIYVQPEQKHTAEYAANITKSVFDYFEEYFAMNYSLPKLDKIAIPDFGTGAMENWGLITYRETNLLYDPKESASSNQQRVATVVAHELVHQWFGNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPIIVTVTTPDEITSVFDGISYSKGSSILRMLEDWIKPENFQKGCQMYLEKYQFKNAKTSDFWAALEEASRLPVKEVMDTWTRQMGYPVLNVNGVKNITQKRFLLDPRANPSQPPSDLGYTWNIPVKWTEDNITSSVLFNRSEKEGITLNSSNPSGNAFLKINPDHIGFYRVNYEVATWDSIATALSLNHKTFSSADRASLIDDAFALARAQLLDYKVALNLTKYLKREENFLPWQRVISAVTYIISMFEDDKELYPMIEEYFQGQVKPIADSLGWNDAGDHVTKLLRSSVLGFACKMGDREALNNASSLFEQWLNGTVSLPVNLRLLVYRYGMQNSGNEISWNYTLEQYQKTSLAQEKEKLLYGLASVKNVTLLSRYLDLLKDTNLIKTQDVFTVIRYISYNSYGKNMAWNWIQLNWDYLVNRYTLNNRNLGRIVTIAEPFNTELQLWQMESFFAKYPQAGAGEKPREQVLETVKNNIEWLKQHRNTIREWFFNLLESG
DRUGINFO
QGC-001
DRUGINFO
EC33
DRUGINFO
KELATORPHAN
DRUGINFO
PMID10602705C40
KEGGPATH
hsa04614:Renin-angiotensin system
WIKIPATH
WP2729:Metabolism of Angiotensinogen to Angiotensins
REACPATH
R-HSA-2022377:Metabolism of Angiotensinogen to Angiotensins
NET_PATH
NetPath_14:IL2 Signaling Pathway
目标的 KEGG 通路数据
标题内容
hsa04614
目标的 Wiki 路径数据
标题内容
WP2729
目标的蛋白质ID
标题内容
TARGETID
UNIPROID
TARGNAME
TARGTYPE
目标的序列数据
标题内容
Glutamyl aminopeptidase (ENPEP)
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