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靶点信息9(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Platelet factor 4 (PF4)
TARGTYPE
Clinical trial target
SYNONYMS
PF-4; C-X-C motif chemokine 4; Iroplact; Oncostatin-A
FUNCTION
Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.
SEQUENCE
MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES
DRUGINFO
Dociparstat sodium
目标的蛋白质ID
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目标的序列数据
标题 | 内容 |
Platelet factor 4 (PF4) |
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