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靶点信息57(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Cationic trypsinogen (PRSS1)
TARGTYPE
Successful target
SYNONYMS
Trypsin-1; Trypsin I; TRYP1; TRY1; TRP1; Serine protease 1; Beta-trypsin
FUNCTION
Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates.
PDBSTRUC
4WXV; 4WWY; 2RA3; 1TRN; 1FXY
SEQUENCE
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
DRUGINFO
Alpha-1 antitrypsin
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04080 |
|
| hsa04972 |
|
| hsa04974 |
|
| hsa05164 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Cationic trypsinogen (PRSS1) |
|