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靶点信息40(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Interleukin 2 receptor beta (IL2RB)
TARGTYPE
Clinical trial target
SYNONYMS
P70-75; Interleukin-2 receptor subunit beta; Interleukin-15 receptor subunit beta; IL15RB; IL-2RB; IL-2R subunit beta; IL-2 receptor subunit beta; IL-2 receptor; High affinity IL-2 receptor subunit beta; CD122
FUNCTION
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15.
PDBSTRUC
6E8K; 5M5E; 4GS7; 3QAZ; 2ERJ
BIOCLASS
Cytokine receptor
SEQUENCE
MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV
DRUGINFO
Leukocyte interleukin
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
KEGGPATH
hsa04144:Endocytosis
KEGGPATH
hsa04151:PI3K-Akt signaling pathway
KEGGPATH
hsa04630:Jak-STAT signaling pathway
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04060 |
|
| hsa04144 |
|
| hsa04151 |
|
| hsa04630 |
|
| hsa05162 |
|
| hsa05166 |
|
| hsa05202 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP49 |
|
| WP453 |
|
| WP2732 |
|
| WP1840 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Interleukin 2 receptor beta (IL2RB) |
|