当前位置：药药网 / 数据中心 /靶点信息(本栏目收费,不能显示细节,电话13136136841)
靶点信息25(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Glutathione-dependent PGD synthase (HPGDS)
TARGTYPE
Successful target
SYNONYMS
HPGDS; Glutathione-S-transferase; GST class-alpha
FUNCTION
Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a widerange of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
PDBSTRUC
6N4E; 5YX1; 5YWX; 5YWE; 5AIX
BIOCLASS
Intramolecular oxidoreductases
SEQUENCE
MPNYKLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSLAIARYLTKNTDLAGNTEMEQCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLTYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKVQAIPAVANWIKRRPQTKL
DRUGINFO
Protoporphyrin IX
DRUGINFO
S-hexylglutathione
KEGGPATH
hsa00590:Arachidonic acid metabolism
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2650 |
|
| WP2586 |
|
| WP2377 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Glutathione-dependent PGD synthase (HPGDS) |
|