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靶点信息21(本栏目收费,不能显示细节,电话13136136841)
靶点信息
UNIPROID
CD80_HUMAN-PD1L1_HUMAN
TARGNAME
CD80-PD-L1 interaction (CD80/PD-L1 PPI)
TARGTYPE
Patented-recorded target
SYNONYMS
T-lymphocyte activation antigen CD80/Programmed cell death 1 ligand 1 PPI
FUNCTION
Augments activated alloreactive CD4+ T cell proliferation and apoptosis and ameliorates acute graft versus host disease
SEQUENCE
MRIFAVFIFMTYWHLLNAFTVTVPKDLYVVEYGSNMTIECKFPVEKQLDLAALIVYWEMEDKNIIQFVHGEEDLKVQHSSYRQRARLLKDQLSLGNAALQITDVKLQDAGVYRCMISYGGADYKRITVKVNAPYNKINQRILVVDPVTSEHELTCQAEGYPKAEVIWTSSDHQVLSGKTTTTNSKREEKLFNVTSTLRINTTTNEIFYCTFRRLDPEENHTAELVIPELPLAHPPNERTHLVILGAILLCLGVALTFIFRLRKGRMMDVKKCGIQDTNSKKQSDTHLEETMGHTRRQGTSPSKCPYLNFFQLLVLAGLSHFCSGVIHVTKEVKEVATLSCGHNVSVEELAQTRIYWQKEKKMVLTMMSGDMNIWPEYKNRTIFDITNNLSIVILALRPSDEGTYECVVLKYEKDAFKREHLAEVTLSVKADFPTPSISDFEIPTSNIRRIICSTSGGFPEPHLSWLENGEELNAINTTVSQDPETELYAVSSKLDFNMTTNHSFMCLIKYGHLRVNQTFNWNTTKQEHFPDNLLPSWAITLISVNGIFVICCLTYCFAPRCRERRRNERLRRESVRPV
DRUGINFO
Biaryl compound 1
DRUGINFO
Biaryl compound 2
DRUGINFO
Macrocycle derivative 1
DRUGINFO
Macrocycle derivative 2
DRUGINFO
Macrocycle derivative 3
DRUGINFO
Macrocycle derivative 4
DRUGINFO
Macrocycle derivative 5
DRUGINFO
Macrocycle derivative 6
DRUGINFO
Macrocycle derivative 7
DRUGINFO
Macrocycle derivative 8
DRUGINFO
Macrocycle derivative 9
DRUGINFO
PMID30107136-Compound-Example11
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| CD80-PD-L1 interaction (CD80/PD-L1 PPI) |
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