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靶点信息23(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Histamine N-methyltransferase (HNMT)
TARGTYPE
Successful target
SYNONYMS
Histamine-N-methyltransferase; HNMT; HMT
FUNCTION
Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine.
PDBSTRUC
2AOX; 2AOW; 2AOV; 2AOU; 2AOT
BIOCLASS
Methyltransferase
SEQUENCE
MASSMRSLFSDHGKYVESFRRFLNHSTEHQCMQEFMDKKLPGIIGRIGDTKSEIKILSIGGGAGEIDLQILSKVQAQYPGVCINNEVVEPSAEQIAKYKELVAKTSNLENVKFAWHKETSSEYQSRMLEKKELQKWDFIHMIQMLYYVKDIPATLKFFHSLLGTNAKMLIIVVSGSSGWDKLWKKYGSRFPQDDLCQYITSDDLTQMLDNLGLKYECYDLLSTMDISDCFIDGNENGDLLWDFLTETCNFNATAPPDLRAELGKDLQEPEFSAKKEGKVLFNNTLSFIVIEA
DRUGINFO
(L-)-S-adenosyl-L-homocysteine
DRUGINFO
4-(DIMETHYLAMINO)BUTYL IMIDOTHIOCARBAMATE
KEGGPATH
hsa00340:Histidine metabolism
WIKIPATH
WP702:Metapathway biotransformation
WIKIPATH
WP704:Methylation Pathways
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
|---|
| Histamine N-methyltransferase (HNMT) |
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