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靶点信息20(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
NKG2-A/B-activating NK receptor (NKG2A)
TARGTYPE
Clinical trial target
SYNONYMS
NKG2A/NKG2B type II integral membrane protein; NKG2A/Bactivating NK receptor; NK cell receptor A; KLRC1; CD159a; CD159 antigenlike family member A
FUNCTION
Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
PDBSTRUC
3CII; 3CDG; 3BDW; 2YU7; 2RMX
SEQUENCE
MDNQGVIYSDLNLPPNPKRQQRKPKGNKNSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL
KEGGPATH
hsa04612:Antigen processing and presentation
KEGGPATH
hsa04650:Natural killer cell mediated cytotoxicity
KEGGPATH
hsa05332:Graft-versus-host disease
WIKIPATH
WP1829:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
REACPATH
R-HSA-198933:Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
NET_PATH
NetPath_11:TCR Signaling Pathway
NET_PATH
NetPath_14:IL2 Signaling Pathway
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04612 |
|
| hsa04650 |
|
| hsa05332 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| NKG2-A/B-activating NK receptor (NKG2A) |
|