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靶点信息31(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Methylmalonyl-CoA mutase (MMUT)
TARGTYPE
Successful target
SYNONYMS
Methylmalonyl-CoA isomerase; MUT; MCM
FUNCTION
Involved in the degradation of several amino acids, odd- chain fatty acids and cholesterol via propionyl-CoA to the tricarboxylic acid cycle. MCM has different functions in other species.
PDBSTRUC
3BIC; 2XIQ; 2XIJ
BIOCLASS
Intramolecular transferases
SEQUENCE
MLRAKNQLFLLSPHYLRQVKESSGSRLIQQRLLHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPEGISIKPLYSKRDTMDLPEELPGVKPFTRGPYPTMYTFRPWTIRQYAGFSTVEESNKFYKDNIKAGQQGLSVAFDLATHRGYDSDNPRVRGDVGMAGVAIDTVEDTKILFDGIPLEKMSVSMTMNGAVIPVLANFIVTGEEQGVPKEKLTGTIQNDILKEFMVRNTYIFPPEPSMKIIADIFEYTAKHMPKFNSISISGYHMQEAGADAILELAYTLADGLEYSRTGLQAGLTIDEFAPRLSFFWGIGMNFYMEIAKMRAGRRLWAHLIEKMFQPKNSKSLLLRAHCQTSGWSLTEQDPYNNIVRTAIEAMAAVFGGTQSLHTNSFDEALGLPTVKSARIARNTQIIIQEESGIPKVADPWGGSYMMECLTNDVYDAALKLINEIEEMGGMAKAVAEGIPKLRIEECAARRQARIDSGSEVIVGVNKYQLEKEDAVEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVAQQAVDADVHAVGISTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGVSNVFGPGTRIPKAAVQVLDDIEKCLEKKQQSV
DRUGINFO
Hydroxocobalamin
KEGGPATH
hsa00280:Valine, leucine and isoleucine degradation
KEGGPATH
hsa00630:Glyoxylate and dicarboxylate metabolism
KEGGPATH
hsa00640:Propanoate metabolism
KEGGPATH
hsa01100:Metabolic pathways
KEGGPATH
hsa01200:Carbon metabolism
WIKIPATH
WP1533:Vitamin B12 Metabolism
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00280 |
|
| hsa00630 |
|
| hsa00640 |
|
| hsa01100 |
|
| hsa01200 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP1857 |
|
| WP1817 |
|
| WP1533 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Methylmalonyl-CoA mutase (MMUT) |
|