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靶点信息31(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
C5a anaphylatoxin chemotactic receptor (C5AR1)
TARGTYPE
Clinical trial target
SYNONYMS
CD88; C5aR; C5a-R; C5a anaphylatoxin chemotactic receptor 1; C5R1
FUNCTION
The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production. Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a.
PDBSTRUC
6C1R; 6C1Q; 5O9H
SEQUENCE
MDSFNYTTPDYGHYDDKDTLDLNTPVDKTSNTLRVPDILALVIFAVVFLVGVLGNALVVWVTAFEAKRTINAIWFLNLAVADFLSCLALPILFTSIVQHHHWPFGGAACSILPSLILLNMYASILLLATISADRFLLVFKPIWCQNFRGAGLAWIACAVAWGLALLLTIPSFLYRVVREEYFPPKVLCGVDYSHDKRRERAVAIVRLVLGFLWPLLTLTICYTFILLRTWSRRATRSTKTLKVVVAVVASFFIFWLPYQVTGIMMSFLEPSSPTFLLLKKLDSLCVSFAYINCCINPIIYVVAGQGFQGRLRKSLPSLLRNVLTEESVVRESKSFTRSTVDTMAQKTQAV
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04080 |
|
| hsa04610 |
|
| hsa05150 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP558 |
|
| WP2806 |
|
| WP24 |
|
| WP1825 |
|
| WP1824 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| C5a anaphylatoxin chemotactic receptor (C5AR1) |
|