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靶点信息22(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Activation-inducible TNFR family receptor (TNFRSF18)
TARGTYPE
Clinical trial target
SYNONYMS
UNQ319/PRO364; Tumor necrosis factor receptor superfamily member 18; Glucocorticoid-induced TNFR-related protein; GITR; CD357; AITR
FUNCTION
Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. Receptor for TNFSF18.
BIOCLASS
Cytokine receptor
SEQUENCE
MAQHGAMGAFRALCGLALLCALSLGQRPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEECCSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLGWLTVVLLAVAACVLLLTSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV
KEGGPATH
hsa04060:Cytokine-cytokine receptor interaction
REACPATH
R-HSA-5669034:TNFs bind their physiological receptors
目标的蛋白质ID
| 标题 | 内容 |
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| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| Activation-inducible TNFR family receptor (TNFRSF18) |
|