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靶点信息45(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Cytotoxic T-lymphocyte protein 4 (CTLA-4)
TARGTYPE
Successful target
SYNONYMS
Cytotoxic T-lymphocyte-associated antigen 4; CTLA-4; CD152
FUNCTION
Inhibitory receptor acting as a major negative regulator of T-cell responses. The affinity of CTLA4 for its natural B7 family ligands, CD80 and CD86, is considerably stronger than the affinity of their cognate stimulatory coreceptor CD28.
PDBSTRUC
5XJ3; 5TRU; 5GGV; 3OSK; 3BX7
SEQUENCE
MACLGFQRHKAQLNLATRTWPCTLLFFLLFIPVFCKAMHVAQPAVVLASSRGIASFVCEYASPGKATEVRVTVLRQADSQVTEVCAATYMMGNELTFLDDSICTGTSSGNQVNLTIQGLRAMDTGLYICKVELMYPPPYYLGIGNGTQIYVIDPEPCPDSDFLLWILAAVSSGLFFYSFLLTAVSLSKMLKKRSPLTTGVYVKMPPTEPECEKQFQPYFIPIN
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04514 |
|
| hsa04660 |
|
| hsa05320 |
|
| hsa05323 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2877 |
|
| WP2583 |
|
| WP2328 |
|
| WP1799 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Cytotoxic T-lymphocyte protein 4 (CTLA-4) |
|