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靶点信息69(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
TARGTYPE
Clinical trial target
SYNONYMS
mcl1/EAT; Bcl2-L-3; Bcl-2-related protein EAT/mcl1; Bcl-2-like protein 3; BCL2L3
FUNCTION
Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis. Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation.
PDBSTRUC
6OVC; 6OQN; 6OQD; 6OQC; 6OQB
BIOCLASS
B-cell lymphoma Bcl-2
SEQUENCE
MFGLKRNAVIGLNLYCGGAGLGAGSGGATRPGGRLLATEKEASARREIGGGEAGAVIGGSAGASPPSTLTPDSRRVARPPPIGAEVPDVTATPARLLFFAPTRRAAPLEEMEAPAADAIMSPEEELDGYEPEPLGKRPAVLPLLELVGESGNNTSTDGSLPSTPPPAEEEEDELYRQSLEIISRYLREQATGAKDTKPMGRSGATSRKALETLRRVGDGVQRNHETAFQGMLRKLDIKNEDDVKSLSRVMIHVFSDGVTNWGRIVTLISFGAFVAKHLKTINQESCIEPLAESITDVLVRTKRDWLVKQRGWDGFVEFFHVEDLEGGIRNVLLAFAGVAGVGAGLAYLIR
DRUGINFO
Biphenyl carboxylic acid derivative 1
DRUGINFO
Biphenyl carboxylic acid derivative 2
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP254 |
|
| WP2005 |
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| WP2004 |
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| WP2003 |
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| WP1772 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) |
|