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靶点信息

标题

内容

相关药物

状态

TARGETID

T13201

FORMERID

TTDR01224

UNIPROID

CAH1_HUMAN

TARGNAME

Carbonic anhydrase I (CA-I)

GENENAME

CA1

TARGTYPE

Successful target

SYNONYMS

Carbonic anhydrase B; Carbonic anhydrase 1; Carbonate dehydratase I; CAB

FUNCTION

Can hydrates cyanamide to urea. Reversible hydration of carbon dioxide.

PDBSTRUC

6HWZ; 6G3V; 6FAG; 6FAF; 6F3B

BIOCLASS

Alpha-carbonic anhydrase

ECNUMBER

EC 4.2.1.1

SEQUENCE

MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF

DRUGINFO

Acetazolamide

DRUGINFO

Dichlorphenamide

DRUGINFO

Ethoxzolamide

DRUGINFO

Methazolamide

DRUGINFO

Salicyclic acid

DRUGINFO

CG-100649

DRUGINFO

Curcumin

DRUGINFO

PARABEN

目标的 KEGG 通路数据

标题	内容
hsa00910	Nitrogen metabolism

目标的 Wiki 路径数据

标题	内容
WP2770	Reversible Hydration of Carbon Dioxide
WP2744	Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes
WP2681	Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes

目标的蛋白质ID

标题	内容
TARGETID	T13201
UNIPROID	CAH1_HUMAN
TARGNAME	Carbonic anhydrase I (CA-I)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Carbonic anhydrase I (CA-I)	MASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAKEIINVGHSFHVNFEDNDNRSVLKGGPFSDSYRLFQFHFHWGSTNEHGSEHTVDGVKYSAELHVAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNFDPSTLLPSSLDFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDNAVPMQHNNRPTQPLKGRTVRASF

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