当前位置：药药网 / 数据中心 /靶点信息(本栏目收费,不能显示细节,电话13136136841)
靶点信息31(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
HSPB1 messenger RNA (HSPB1 mRNA)
TARGTYPE
Discontinued target
SYNONYMS
Stress-responsive protein 27 (mRNA); SRP27 (mRNA); HspB1 (mRNA); Heat shock protein beta-1 (mRNA); Heat shock 27 kDa protein (mRNA); HSP28 (mRNA); HSP 27 (mRNA); Estrogen-regulated 24 kDa protein (mRNA); 28 kDa heat shock protein (mRNA)
FUNCTION
Plays a role in stress resistance and actin organization. Through its molecular chaperone activity may regulate numerous biological processes including the phosphorylation and the axonal transport of neurofilament proteins. Small heat shock protein which functions as a molecular chaperone probably maintaining denatured proteins in a folding-competent state.
PDBSTRUC
4MJH; 3Q9Q; 3Q9P; 2N3J
SEQUENCE
MTERRVPFSLLRGPSWDPFRDWYPHSRLFDQAFGLPRLPEEWSQWLGGSSWPGYVRPLPPAAIESPAVAAPAYSRALSRQLSSGVSEIRHTADRWRVSLDVNHFAPDELTVKTKDGVVEITGKHEERQDEHGYISRCFTRKYTLPPGVDPTQVSSSLSPEGTLTVEAPMPKLATQSNEITIPVTFESRAQLGGPEAAKSDETAAK
DRUGINFO
OGX-427 + Paclitaxel
KEGGPATH
hsa04010:MAPK signaling pathway
KEGGPATH
hsa04370:VEGF signaling pathway
KEGGPATH
hsa05146:Amoebiasis
KEGGPATH
hsa05169:Epstein-Barr virus infection
WIKIPATH
WP2733:Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
WIKIPATH
WP2864:Apoptosis-related network due to altered Notch3 in ovarian cancer
WIKIPATH
WP314:FAS pathway and Stress induction of HSP regulation
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04010 |
|
| hsa04370 |
|
| hsa05146 |
|
| hsa05169 |
|
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP400 |
|
| WP382 |
|
| WP314 |
|
| WP2864 |
|
| WP2733 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| HSPB1 messenger RNA (HSPB1 mRNA) |
|