当前位置：药药网 / 数据中心 /靶点信息(本栏目收费,不能显示细节,电话13136136841)
靶点信息25(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Corticotropin-releasing factor receptor 2 (CRHR2)
TARGTYPE
Clinical trial target
SYNONYMS
Corticotropin-releasinghormone receptor 2; CRHR2; CRH2 receptor; CRH-R 2; CRF2; CRF-R 2
FUNCTION
This is a receptor for corticotropin releasing factor. Shows high-affinity crf binding. Also binds to urocortin i, ii and iii. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
PDBSTRUC
3N96; 3N95; 3N93
SEQUENCE
MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
KEGGPATH
hsa04080:Neuroactive ligand-receptor interaction
WIKIPATH
WP1824:GPCR downstream signaling
WIKIPATH
WP1825:GPCR ligand binding
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP334 |
|
| WP2355 |
|
| WP1825 |
|
| WP1824 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Corticotropin-releasing factor receptor 2 (CRHR2) |
|