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靶点信息17(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Alpha-fetoprotein (AFP)
TARGTYPE
Clinical trial target
SYNONYMS
Alpha-fetoglobulin; Alpha-1-fetoprotein; AFP
FUNCTION
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
BIOCLASS
Serum albumin family
SEQUENCE
MKWVESIFLIFLLNFTESRTLHRNEYGIASILDSYQCTAEISLADLATIFFAQFVQEATYKEVSKMVKDALTAIEKPTGDEQSSGCLENQLPAFLEELCHEKEILEKYGHSDCCSQSEEGRHNCFLAHKKPTPASIPLFQVPEPVTSCEAYEEDRETFMNKFIYEIARRHPFLYAPTILLWAARYDKIIPSCCKAENAVECFQTKAATVTKELRESSLLNQHACAVMKNFGTRTFQAITVTKLSQKFTKVNFTEIQKLVLDVAHVHEHCCRGDVLDCLQDGEKIMSYICSQQDTLSNKITECCKLTTLERGQCIIHAENDEKPEGLSPNLNRFLGDRDFNQFSSGEKNIFLASFVHEYSRRHPQLAVSVILRVAKGYQELLEKCFQTENPLECQDKGEEELQKYIQESQALAKRSCGLFQKLGEYYLQNAFLVAYTKKAPQLTSSELMAITRKMAATAATCCQLSEDKLLACGEGAADIIIGHLCIRHEMTPVNPGVGQCCTSSYANRRPCFSSLVVDETYVPPAFSDDKFIFHKDLCQAQGVALQTMKQEFLINLVKQKPQITEEQLEAVIADFSGLLEKCCQGQEQEVCFAEEGQKLISKTRAALGV
KEGGPATH
hsa04390:Hippo signaling pathway
INTEPATH
hnf3bpathway:FOXA2 and FOXA3 transcription factor networks
INTEPATH
p53downstreampathway:Direct p53 effectors
INTEPATH
p73pathway:p73 transcription factor network
INTEPATH
reg_gr_pathway:Glucocorticoid receptor regulatory network
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Alpha-fetoprotein (AFP) |
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