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靶点信息53(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Prostaglandin E synthase (PTGES)
TARGTYPE
Clinical trial target
SYNONYMS
p53-induced gene 12 protein; PIG12; PGES; PGE synthase; P53-induced apoptosis protein 12; Microsomal prostaglandin E synthase 1; Microsomal glutathione S-transferase 1-like 1; MPGES1; MPGES-1; MGST1L1; MGST1-L1
FUNCTION
Catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2).
PDBSTRUC
5TL9; 5T37; 5T36; 5K0I; 5BQI
BIOCLASS
Intramolecular oxidoreductase
SEQUENCE
MPAHSLVMSSPALPAFLLCSTLLVIKMYVVAIITGQVRLRKKAFANPEDALRHGGPQYCRSDPDVERCLRAHRNDMETIYPFLFLGFVYSFLGPNPFVAWMHFLVFLVGRVAHTVAYLGKLRAPIRSVTYTLAQLPCASMALQILWEAARHL
DRUGINFO
Alpha-substituted pirinixic acid and pirinixic acid ester derivative 1
DRUGINFO
Benzamide derivative 14
DRUGINFO
Benzamide derivative 15
DRUGINFO
Benzamide derivative 16
DRUGINFO
Benzamide derivative 18
DRUGINFO
Benzimidazole derivative 11
DRUGINFO
Benzimidazole derivative 12
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
|---|
| Prostaglandin E synthase (PTGES) |
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