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靶点信息23(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
T-cell surface antigen CD2 (CD2)
TARGTYPE
Clinical trial target
SYNONYMS
T-cell surface antigen T11/Leu-5; SRBC; Rosette receptor; LFA-3 receptor; LFA-2; Erythrocyte receptor
FUNCTION
CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function. CD2 interacts with lymphocyte function-associated antigen CD58 (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types.
PDBSTRUC
2J7I; 2J6O; 1QA9; 1L2Z; 1HNF
SEQUENCE
MSFPCKFVASFLLIFNVSSKGAVSKEITNALETWGALGQDINLDIPSFQMSDDIDDIKWEKTSDKKKIAQFRKEKETFKEKDTYKLFKNGTLKIKHLKTDDQDIYKVSIYDTKGKNVLEKIFDLKIQERVSKPKISWTCINTTLTCEVMNGTDPELNLYQDGKHLKLSQRVITHKWTTSLSAKFKCTAGNKVSKESSVEPVSCPEKGLDIYLIIGICGGGSLLMVFVALLVFYITKRKKQRSRRNDEELETRAHRVATEERGRKPHQIPASTPQNPATSQHPPPPPGHRSQAPSHRPPPPGHRVQHQPQKRPPAPSGTQVHQQKGPPLPRPRVQPKPPHGAAENSLSPSSN
DRUGINFO
Cyclo(1,10)EIYDPGDDIK
DRUGINFO
Cyclo(1,10)H-EIYDPGDDIK-OH
DRUGINFO
Cyclo(1,11)H-ESIYDPGDDIK-OH
DRUGINFO
Cyclo(1,12)PenIYDTKGKNVLC-OH
DRUGINFO
Pen(Acm)AQFRKEKETFC(Acm)-OH
KEGGPATH
hsa04514:Cell adhesion molecules (CAMs)
KEGGPATH
hsa04640:Hematopoietic cell lineage
WIKIPATH
WP1794:Cell surface interactions at the vascular wall
目标的蛋白质ID
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目标的序列数据
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| T-cell surface antigen CD2 (CD2) |
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