靶点信息26(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Glutamate--cysteine ligase modifier (GCLM)
TARGTYPE
Literature-reported target
SYNONYMS
Glutamate--cysteine ligase modifier subunit; Gamma-glutamylcysteine synthetase regulatory subunit; Gamma-ECS regulatory subunit; GCS light chain
FUNCTION
cytosol, glutamate-cysteine ligase complex, enzyme regulator activity, glutamate-cysteine ligase catalytic subunit binding, glutamate metabolic process, glutathione biosynthetic process, positive regulation of glutamate-cysteine ligase activity, regulation of blood vessel size, response to drug, response to oxidative stress.
BIOCLASS
Aldo/keto reductase family
SEQUENCE
MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
DRUGINFO
Buthionine sulfoximine
DRUGINFO
N-Formylmethionine
KEGGPATH
hsa00480:Glutathione metabolism
KEGGPATH
hsa01100:Metabolic pathways
WIKIPATH
WP100:Glutathione metabolism
WIKIPATH
WP1880:Phase II conjugation
WIKIPATH
WP2333:Trans-sulfuration pathway
WIKIPATH
WP2525:Trans-sulfuration and one carbon metabolism
WIKIPATH
WP2693:Metabolism of amino acids and derivatives
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP3 |
|
| WP2884 |
|
| WP2882 |
|
| WP2693 |
|
| WP2525 |
|
| WP2333 |
|
| WP1880 |
|
| WP100 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| Glutamate--cysteine ligase modifier (GCLM) |
|