TARGETID

T01777

FORMERID

TTDR01180

UNIPROID

ADA2C_HUMAN

TARGNAME

Adrenergic receptor alpha-2C (ADRA2C)

GENENAME

ADRA2C

TARGTYPE

Successful target

SYNONYMS

Subtype C4; Alpha-2CAR; Alpha-2C adrenoreceptor; Alpha-2C adrenoceptor; Alpha-2C adrenergic receptor; Alpha-2 adrenergic receptor subtype C4; ADRA2RL2; ADRA2L2

FUNCTION

Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins.

BIOCLASS

GPCR rhodopsin

SEQUENCE

MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGFLIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFGQVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISAVISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLRTRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGALRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRRRRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFKFFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ

DRUGINFO

Amezinium

DRUGINFO

Amosulalol

DRUGINFO

Brimonidine

DRUGINFO

Dihydroergocristine

DRUGINFO

MOXONIDINE

DRUGINFO

Propylhexedrine

DRUGINFO

Rilmenidine

DRUGINFO

Tetrahydrozoline

DRUGINFO

Xylometazoline

DRUGINFO

IDAZOXAN HYDROCHLORIDE