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靶点信息63(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase)
GENENAME
Malaria DHOdehase
TARGTYPE
Successful target
SYNONYMS
PFF0160c; Mitochondrially bound dihydroorotate-ubiqui oxidoreductase; Dihydroorotate oxidase of Plasmodium falciparum; Dihydroorotate dehydrogenase of Plasmodium falciparum; DHOdehase of Plasmodium falciparum; DHODase; DHODH of Plasmodium falciparum; DHOD
FUNCTION
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
PDBSTRUC
6GJG; 6E0B; 5TBO; 5FI8; 5DEL
BIOCLASS
CH-CH donor oxidoreductase
SEQUENCE
MISKLKPQFMFLPKKHILSYCRKDVLNLFEQKFYYTSKRKESNNMKNESLLRLINYNRYYNKIDSNNYYNGGKILSNDRQYIYSPLCEYKKKINDISSYVSVPFKINIRNLGTSNFVNNKKDVLDNDYIYENIKKEKSKHKKIIFLLFVSLFGLYGFFESYNPEFFLYDIFLKFCLKYIDGEICHDLFLLLGKYNILPYDTSNDSIYACTNIKHLDFINPFGVAAGFDKNGVCIDSILKLGFSFIEIGTITPRGQTGNAKPRIFRDVESRSIINSCGFNNMGCDKVTENLILFRKRQEEDKLLSKHIVGVSIGKNKDTVNIVDDLKYCINKIGRYADYIAINVSSPNTPGLRDNQEAGKLKNIILSVKEEIDNLEKNNIMNDESTYNEDNKIVEKKNNFNKNNSHMMKDAKDNFLWFNTTKKKPLVFVKLAPDLNQEQKKEIADVLLETNIDGMIISNTTTQINDIKSFENKKGGVSGAKLKDISTKFICEMYNYTNKQIPIIASGGIFSGLDALEKIEAGASVCQLYSCLVFNGMKSAVQIKRELNHLLYQRGYYNLKEAIGRKHSKS
DRUGINFO
Avastin+/-Tarceva
DRUGINFO
1,4-Naphthoquinone
DRUGINFO
1-hydroxy-2-dodecyl-4(1H)quinolone
DRUGINFO
2-(2-bromo-2-naphthamido)benzoic acid
目标的蛋白质ID
| 标题 | 内容 |
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| TARGETID |
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| UNIPROID |
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| TARGNAME |
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| TARGTYPE |
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目标的序列数据
| 标题 | 内容 |
|---|
| Plasmodium Dihydroorotate dehydrogenase (Malaria DHOdehase) |
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