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靶点信息

标题

内容

相关药物

状态

TARGETID

T00902

FORMERID

TTDI02363

UNIPROID

NTF4_HUMAN

TARGNAME

Neurotrophin-4 (NTF4)

GENENAME

NTF4

TARGTYPE

Literature-reported target

SYNONYMS

Neutrophic factor 4; Neurotrophin5; Neurotrophin4; Neurotrophin-5; NTF5; NT4; NT-5; NT-4

FUNCTION

Target-derived survival factor for peripheral sensory sympathetic neurons.

PDBSTRUC

1HCF; 1B98; 1B8M

BIOCLASS

Growth factor

SEQUENCE

MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA

DRUGINFO

D0P3SH

ReN-1826

Terminated

KEGGPATH

hsa04010:MAPK signaling pathway

KEGGPATH

hsa04722:Neurotrophin signaling pathway

WIKIPATH

WP2848:Differentiation Pathway

WIKIPATH

WP382:MAPK Signaling Pathway

NET_PATH

NetPath_9:TNFalpha Signaling Pathway

INTEPATH

p75ntrpathway:p75(NTR)-mediated signaling

INTEPATH

shp2_pathway:SHP2 signaling

INTEPATH

trkrpathway:Neurotrophic factor-mediated Trk receptor signaling

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04722	Neurotrophin signaling pathway

目标的 Wiki 路径数据

标题	内容
WP382	MAPK Signaling Pathway
WP2848	Differentiation Pathway

目标的蛋白质ID

标题	内容
TARGETID	T00902
UNIPROID	NTF4_HUMAN
TARGNAME	Neurotrophin-4 (NTF4)
TARGTYPE	Research target

目标的序列数据

标题	内容
Neurotrophin-4 (NTF4)	MLPLPSCSLPILLLFLLPSVPIESQPPPSTLPPFLAPEWDLLSPRVVLSRGAPAGPPLLFLLEAGAFRESAGAPANRSRRGVSETAPASRRGELAVCDAVSGWVTDRRTAVDLRGREVEVLGEVPAAGGSPLRQYFFETRCKADNAEEGGPGAGGGGCRGVDRRHWVSECKAKQSYVRALTADAQGRVGWRWIRIDTACVCTLLSRTGRA

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