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靶点信息218(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Arachidonate 5-lipoxygenase (5-LOX)
TARGTYPE
Successful target
SYNONYMS
LOG5; 5-lipoxygenase; 5-LO
FUNCTION
Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.
PDBSTRUC
3V99; 3V98; 3V92; 3O8Y; 2ABV
SEQUENCE
MPSYTVTVATGSQWFAGTDDYIYLSLVGSAGCSEKHLLDKPFYNDFERGAVDSYDVTVDEELGEIQLVRIEKRKYWLNDDWYLKYITLKTPHGDYIEFPCYRWITGDVEVVLRDGRAKLARDDQIHILKQHRRKELETRQKQYRWMEWNPGFPLSIDAKCHKDLPRDIQFDSEKGVDFVLNYSKAMENLFINRFMHMFQSSWNDFADFEKIFVKISNTISERVMNHWQEDLMFGYQFLNGCNPVLIRRCTELPEKLPVTTEMVECSLERQLSLEQEVQQGNIFIVDFELLDGIDANKTDPCTLQFLAAPICLLYKNLANKIVPIAIQLNQIPGDENPIFLPSDAKYDWLLAKIWVRSSDFHVHQTITHLLRTHLVSEVFGIAMYRQLPAVHPIFKLLVAHVRFTIAINTKAREQLICECGLFDKANATGGGGHVQMVQRAMKDLTYASLCFPEAIKARGMESKEDIPYYFYRDDGLLVWEAIRTFTAEVVDIYYEGDQVVEEDPELQDFVNDVYVYGMRGRKSSGFPKSVKSREQLSEYLTVVIFTASAQHAAVNFGQYDWCSWIPNAPPTMRAPPPTAKGVVTIEQIVDTLPDRGRSCWHLGAVWALSQFQENELFLGMYPEEHFIEKPVKEAMARFRKNLEAIVSVIAERNKKKQLPYYYLSPDRIPNSVAI
DRUGINFO
Diethylcarbamazine
DRUGINFO
3,4-Dihydroxycinnamic Acid
DRUGINFO
Avastin+/-Tarceva
目标的 KEGG 通路数据
标题 | 内容 |
hsa00590 |
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hsa01100 |
|
hsa04726 |
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hsa04913 |
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hsa05145 |
|
目标的 Wiki 路径数据
标题 | 内容 |
WP2877 |
|
WP2650 |
|
WP167 |
|
WP15 |
|
目标的蛋白质ID
标题 | 内容 |
TARGETID |
|
UNIPROID |
|
TARGNAME |
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TARGTYPE |
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目标的序列数据
标题 | 内容 |
Arachidonate 5-lipoxygenase (5-LOX) |
|