靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WHIZPATH

PW000446:Intracellular Signalling Through Adenosine Receptor A2b and Adenosine

REACPATH

R-HSA-1295596:Spry regulation of FGF signaling

REACPATH

R-HSA-170968:Frs2-mediated activation

REACPATH

R-HSA-170984:ARMS-mediated activation

REACPATH

R-HSA-442742:CREB phosphorylation through the activation of Ras

REACPATH

R-HSA-5673000:RAF activation

REACPATH

R-HSA-5674135:MAP2K and MAPK activation

REACPATH

R-HSA-5674499:Negative feedback regulation of MAPK pathway

REACPATH

R-HSA-5675221:Negative regulation of MAPK pathway

NET_PATH

NetPath_19:IL-7 Signaling Pathway

INTEPATH

cdc42_pathway:CDC42 signaling events

INTEPATH

erbb1_downstream_pathway:ErbB1 downstream signaling

INTEPATH

mapktrkpathway:Trk receptor signaling mediated by the MAPK pathway

INTEPATH

mtor_4pathway:mTOR signaling pathway

INTEPATH

pdgfrbpathway:PDGFR-beta signaling pathway

INTEPATH

tcrraspathway:Ras signaling in the CD4+ TCR pathway

INTEPATH

vegfr1_2_pathway:Signaling events mediated by VEGFR1 and VEGFR2

PANTPATH

P00005:Angiogenesis

PANTPATH

P00034:Integrin signalling pathway

PANTPATH

P00036:Interleukin signaling pathway

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04015	Rap1 signaling pathway
hsa04024	cAMP signaling pathway
hsa04062	Chemokine signaling pathway
hsa04068	FoxO signaling pathway
hsa04150	mTOR signaling pathway
hsa04270	Vascular smooth muscle contraction
hsa04510	Focal adhesion
hsa04650	Natural killer cell mediated cytotoxicity
hsa04720	Long-term potentiation
hsa04722	Neurotrophin signaling pathway
hsa04726	Serotonergic synapse
hsa04730	Long-term depression
hsa04810	Regulation of actin cytoskeleton
hsa04910	Insulin signaling pathway
hsa04914	Progesterone-mediated oocyte maturation
hsa05034	Alcoholism
hsa05160	Hepatitis C
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer
hsa05210	Colorectal cancer
hsa05211	Renal cell carcinoma
hsa05212	Pancreatic cancer
hsa05213	Endometrial cancer
hsa05214	Glioma
hsa05215	Prostate cancer
hsa05216	Thyroid cancer
hsa05218	Melanoma
hsa05219	Bladder cancer
hsa05220	Chronic myeloid leukemia
hsa05221	Acute myeloid leukemia
hsa05223	Non-small cell lung cancer

目标的 Wiki 路径数据

标题	内容
WP734	Serotonin Receptor 4/6/7 and NR3C Signaling
WP722	Serotonin HTR1 Group and FOS Pathway
WP712	Estrogen signaling pathway
WP615	Senescence and Autophagy in Cancer
WP51	Regulation of Actin Cytoskeleton
WP437	EGF/EGFR Signaling Pathway
WP422	MAPK Cascade
WP382	MAPK Signaling Pathway
WP306	Focal Adhesion
WP2828	Bladder Cancer
WP2754	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
WP2571	Polycystic Kidney Disease Pathway
WP2355	Corticotropin-releasing hormone
WP23	B Cell Receptor Signaling Pathway
WP2261	Signaling Pathways in Glioblastoma
WP2032	TSH signaling pathway
WP1984	Integrated Breast Cancer Pathway
WP1911	Signaling by FGFR
WP1873	NGF signalling via TRKA from the plasma membrane
WP185	Integrin-mediated Cell Adhesion

目标的蛋白质ID

标题	内容
TARGETID	T99089
UNIPROID	BRAF_HUMAN
TARGNAME	Serine/threonine-protein kinase B-raf (BRAF)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Serine/threonine-protein kinase B-raf (BRAF)	MAALSGGGGGGAEPGQALFNGDMEPEAGAGAGAAASSAADPAIPEEVWNIKQMIKLTQEHIEALLDKFGGEHNPPSIYLEAYEEYTSKLDALQQREQQLLESLGNGTDFSVSSSASMDTVTSSSSSSLSVLPSSLSVFQNPTDVARSNPKSPQKPIVRVFLPNKQRTVVPARCGVTVRDSLKKALMMRGLIPECCAVYRIQDGEKKPIGWDTDISWLTGEELHVEVLENVPLTTHNFVRKTFFTLAFCDFCRKLLFQGFRCQTCGYKFHQRCSTEVPLMCVNYDQLDLLFVSKFFEHHPIPQEEASLAETALTSGSSPSAPASDSIGPQILTSPSPSKSIPIPQPFRPADEDHRNQFGQRDRSSSAPNVHINTIEPVNIDDLIRDQGFRGDGGSTTGLSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNVTAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDLKSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIFMVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQAGGYGAFPVH

标题

内容

Serine/threonine-protein kinase B-raf (BRAF)

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