靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WHIZPATH

PW000441:Excitatory Neural Signalling Through 5-HTR 4 and Serotonin

WHIZPATH

PW000442:Corticotropin Activation of Cortisol Production

WHIZPATH

PW000443:Excitatory Neural Signalling Through 5-HTR 7 and Serotonin

WHIZPATH

PW000444:Excitatory Neural Signalling Through 5-HTR 6 and Serotonin

WHIZPATH

PW000445:Intracellular Signalling Through Adenosine Receptor A2a and Adenosine

WHIZPATH

PW000446:Intracellular Signalling Through Adenosine Receptor A2b and Adenosine

WHIZPATH

PW000447:Vasopressin Regulation of Water Homeostasis

WHIZPATH

PW000448:Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone

WHIZPATH

PW000449:Intracellular Signalling Through Histamine H2 Receptor and Histamine

WHIZPATH

PW000450:Intracellular Signalling Through LHCGR Receptor and Luteinizing Hormone/Choriogonadotropin

WHIZPATH

PW000451:Intracellular Signalling Through PGD2 receptor and Prostaglandin D2

WHIZPATH

PW000452:Intracellular Signalling Through Prostacyclin Receptor and Prostacyclin

REACPATH

R-HSA-163359:Glucagon signaling in metabolic regulation

REACPATH

R-HSA-163615:PKA activation

REACPATH

R-HSA-164378:PKA activation in glucagon signalling

REACPATH

R-HSA-418555:G alpha (s) signalling events

REACPATH

R-HSA-418594:G alpha (i) signalling events

REACPATH

R-HSA-418597:G alpha (z) signalling events

REACPATH

R-HSA-432040:Vasopressin regulates renal water homeostasis via Aquaporins

REACPATH

R-HSA-5610787:Hedgehog 'off' state

目标的 KEGG 通路数据

标题	内容
hsa00230	Purine metabolism
hsa04015	Rap1 signaling pathway
hsa04020	Calcium signaling pathway
hsa04022	cGMP-PKG signaling pathway
hsa04024	cAMP signaling pathway
hsa04062	Chemokine signaling pathway
hsa04114	Oocyte meiosis
hsa04261	Adrenergic signaling in cardiomyocytes
hsa04270	Vascular smooth muscle contraction
hsa04540	Gap junction
hsa04611	Platelet activation
hsa04713	Circadian entrainment
hsa04723	Retrograde endocannabinoid signaling
hsa04724	Glutamatergic synapse
hsa04725	Cholinergic synapse
hsa04727	GABAergic synapse
hsa04750	Inflammatory mediator regulation of TRP channels
hsa04911	Insulin secretion
hsa04912	GnRH signaling pathway
hsa04913	Ovarian steroidogenesis
hsa04914	Progesterone-mediated oocyte maturation
hsa04915	Estrogen signaling pathway
hsa04916	Melanogenesis
hsa04918	Thyroid hormone synthesis
hsa04921	Oxytocin signaling pathway
hsa04922	Glucagon signaling pathway
hsa04923	Regulation of lipolysis in adipocytes
hsa04970	Salivary secretion
hsa04971	Gastric acid secretion
hsa04972	Pancreatic secretion
hsa04976	Bile secretion
hsa05032	Morphine addiction
hsa05166	HTLV-I infection
hsa05200	Pathways in cancer
hsa05414	Dilated cardiomyopathy

目标的 Wiki 路径数据

标题	内容
WP536	Calcium Regulation in the Cardiac Cell
WP35	G Protein Signaling Pathways
WP289	Myometrial Relaxation and Contraction Pathways
WP2754	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
WP2688	DAG and IP3 signaling
WP2662	Regulation of Water Balance by Renal Aquaporins
WP2032	TSH signaling pathway
WP1978	Opioid Signalling
WP1831	Integration of energy metabolism
WP1824	GPCR downstream signaling
WP1602	Nicotine Activity on Dopaminergic Neurons

目标的蛋白质ID

标题	内容
TARGETID	T97655
UNIPROID	ADCY2_HUMAN
TARGNAME	Adenylate cyclase type 2 (ADCY2)
TARGTYPE	Research target

目标的序列数据

标题	内容
Adenylate cyclase type 2 (ADCY2)	MWQEAMRRRRYLRDRSEEAAGGGDGLPRSRDWLYESYYCMSQQHPLIVFLLLIVMGSCLALLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICLVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSATPGGKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKVLEKEYRATALPAFKYYVTCACLIFFCIFIVQILVLPKTSVLGISFGAAFLLLAFILFVCFAGQLLQCSKKASPLLMWLLKSSGIIANRPWPRISLTIITTAIILMMAVFNMFFLSDSEETIPPTANTTNTSFSASNNQVAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTILLHTHAHVLGDYSQVLFERPGIWKDLKTMGSVSLSIFFITLLVLGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQSNVAS

标题

内容

Adenylate cyclase type 2 (ADCY2)

MWQEAMRRRRYLRDRSEEAAGGGDGLPRSRDWLYESYYCMSQQHPLIVFLLLIVMGSCLALLAVFFALGLEVEDHVAFLITVPTALAIFFAIFILVCIESVFKKLLRLFSLVIWICLVAMGYLFMCFGGTVSPWDQVSFFLFIIFVVYTMLPFNMRDAIIASVLTSSSHTIVLSVCLSATPGGKEHLVWQILANVIIFICGNLAGAYHKHLMELALQQTYQDTCNCIKSRIKLEFEKRQQERLLLSLLPAHIAMEMKAEIIQRLQGPKAGQMENTNNFHNLYVKRHTNVSILYADIVGFTRLASDCSPGELVHMLNELFGKFDQIAKENECMRIKILGDCYYCVSGLPISLPNHAKNCVKMGLDMCEAIKKVRDATGVDINMRVGVHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRVHISSVTLEHLNGAYKVEEGDGDIRDPYLKQHLVKTYFVINPKGERRSPQHLFRPRHTLDGAKMRASVRMTRYLESWGAAKPFAHLHHRDSMTTENGKISTTDVPMGQHNFQNRTLRTKSQKKRFEEELNERMIQAIDGINAQKQWLKSEDIQRISLLFYNKVLEKEYRATALPAFKYYVTCACLIFFCIFIVQILVLPKTSVLGISFGAAFLLLAFILFVCFAGQLLQCSKKASPLLMWLLKSSGIIANRPWPRISLTIITTAIILMMAVFNMFFLSDSEETIPPTANTTNTSFSASNNQVAILRAQNLFFLPYFIYSCILGLISCSVFLRVNYELKMLIMMVALVGYNTILLHTHAHVLGDYSQVLFERPGIWKDLKTMGSVSLSIFFITLLVLGRQNEYYCRLDFLWKNKFKKEREEIETMENLNRVLLENVLPAHVAEHFLARSLKNEELYHQSYDCVCVMFASIPDFKEFYTESDVNKEGLECLRLLNEIIADFDDLLSKPKFSGVEKIKTIGSTYMAATGLSAVPSQEHSQEPERQYMHIGTMVEFAFALVGKLDAINKHSFNDFKLRVGINHGPVIAGVIGAQKPQYDIWGNTVNVASRMDSTGVLDKIQVTEETSLVLQTLGYTCTCRGIINVKGKGDLKTYFVNTEMSRSLSQSNVAS

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