靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

REACPATH

R-HSA-416482:G alpha (12/13) signalling events

REACPATH

R-HSA-416550:Sema4D mediated inhibition of cell attachment and migration

REACPATH

R-HSA-416572:Sema4D induced cell migration and growth-cone collapse

REACPATH

R-HSA-4420097:VEGFA-VEGFR2 Pathway

REACPATH

R-HSA-5625740:RHO GTPases activate PKNs

REACPATH

R-HSA-5625900:RHO GTPases activate CIT

REACPATH

R-HSA-5627117:RHO GTPases Activate ROCKs

REACPATH

R-HSA-5663220:RHO GTPases Activate Formins

INTEPATH

a4b7_pathway:a4b7 Integrin signaling

INTEPATH

amb2_neutrophils_pathway:amb2 Integrin signaling

INTEPATH

arf6downstreampathway:Arf6 downstream pathway

INTEPATH

aurora_b_pathway:Aurora B signaling

INTEPATH

avb3_integrin_pathway:Integrins in angiogenesis

INTEPATH

avb3_opn_pathway:Osteopontin-mediated events

INTEPATH

cxcr4_pathway:CXCR4-mediated signaling events

INTEPATH

ecadherin_keratinocyte_pathway:E-cadherin signaling in keratinocytes

INTEPATH

ecadherin_nascentaj_pathway:E-cadherin signaling in the nascent adherens junction

INTEPATH

ecadherin_stabilization_pathway:Stabilization and expansion of the E-cadherin adherens junction

INTEPATH

endothelinpathway:Endothelins

INTEPATH

epha_fwdpathway:EPHA forward signaling

目标的 KEGG 通路数据

标题	内容
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04022	cGMP-PKG signaling pathway
hsa04024	cAMP signaling pathway
hsa04062	Chemokine signaling pathway
hsa04071	Sphingolipid signaling pathway
hsa04144	Endocytosis
hsa04270	Vascular smooth muscle contraction
hsa04310	Wnt signaling pathway
hsa04350	TGF-beta signaling pathway
hsa04360	Axon guidance
hsa04510	Focal adhesion
hsa04520	Adherens junction
hsa04530	Tight junction
hsa04611	Platelet activation
hsa04660	T cell receptor signaling pathway
hsa04670	Leukocyte transendothelial migration
hsa04722	Neurotrophin signaling pathway
hsa04810	Regulation of actin cytoskeleton
hsa04921	Oxytocin signaling pathway
hsa04972	Pancreatic secretion
hsa05100	Bacterial invasion of epithelial cells
hsa05130	Pathogenic Escherichia coli infection
hsa05133	Pertussis
hsa05152	Tuberculosis
hsa05200	Pathways in cancer
hsa05203	Viral carcinogenesis
hsa05205	Proteoglycans in cancer
hsa05206	MicroRNAs in cancer
hsa05210	Colorectal cancer

目标的 Wiki 路径数据

标题	内容
WP722	Serotonin HTR1 Group and FOS Pathway
WP710	DNA Damage Response (only ATM dependent)
WP524	G13 Signaling Pathway
WP51	Regulation of Actin Cytoskeleton
WP428	Wnt Signaling Pathway
WP399	Wnt Signaling Pathway and Pluripotency
WP366	TGF beta Signaling Pathway
WP363	Wnt Signaling Pathway Netpath
WP35	G Protein Signaling Pathways
WP306	Focal Adhesion
WP2742	Signaling by TGF-beta Receptor Complex
WP2593	JAK/STAT
WP244	Alpha 6 Beta 4 signaling pathway
WP2431	Spinal Cord Injury
WP2355	Corticotropin-releasing hormone
WP2324	AGE/RAGE pathway
WP2272	Pathogenic Escherichia coli infection
WP2034	Leptin signaling pathway
WP1976	Signalling by NGF
WP1917	Signaling by Rho GTPases
WP1907	Semaphorin interactions
WP1873	NGF signalling via TRKA from the plasma membrane
WP1826	GPVI-mediated activation cascade
WP1824	GPCR downstream signaling
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP1528	Physiological and Pathological Hypertrophy of the Heart
WP138	Androgen receptor signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T96736
UNIPROID	RHOA_HUMAN
TARGNAME	Transforming protein RhoA (RHOA)
TARGTYPE	Discontinued target

目标的序列数据

标题	内容
Transforming protein RhoA (RHOA)	MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDTAGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKDLRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQARRGKKKSGCLVL

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