靶点信息20(本栏目收费,不能显示细节,电话13136136841)
靶点信息
标题
内容
相关药物
状态
TARGETID
T95302
FORMERID
TTDI02123
UNIPROID
MC5R_HUMAN
TARGNAME
Melanocortin receptor 5 (MC5R)
GENENAME
MC5R
TARGTYPE
Clinical trial target
SYNONYMS
MC5-R; MC2; MC-2
FUNCTION
The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins. Receptor for MSH (alpha, beta and gamma) and ACTH.
BIOCLASS
GPCR rhodopsin
SEQUENCE
MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
DRUGINFO
JNJ-10229570
DRUGINFO
MTC-896
DRUGINFO
MT-II
KEGGPATH
hsa04080:Neuroactive ligand-receptor interaction
WIKIPATH
WP1824:GPCR downstream signaling
WIKIPATH
WP1825:GPCR ligand binding
WIKIPATH
WP24:Peptide GPCRs
WIKIPATH
WP455:GPCRs, Class A Rhodopsin-like
REACPATH
R-HSA-375276:Peptide ligand-binding receptors
REACPATH
R-HSA-418555:G alpha (s) signalling events
目标的 KEGG 通路数据
标题内容
hsa04080
目标的 Wiki 路径数据
标题内容
WP455
WP24
WP1825
WP1824
目标的蛋白质ID
标题内容
TARGETID
UNIPROID
TARGNAME
TARGTYPE
目标的序列数据
标题内容
Melanocortin receptor 5 (MC5R)
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