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靶点信息

标题

内容

相关药物

状态

TARGETID

T93955

FORMERID

TTDS00506

UNIPROID

MTLD_ASPFU

TARGNAME

Aspergillus Mannitol-1-phosphate 5-dehydrogenase (Asperg mpdA)

GENENAME

Asperg mpdA

TARGTYPE

Successful target

SYNONYMS

mpdA; MPDH; MPD; M1PDH

FUNCTION

Catalyzes the NAD(H)-dependent interconversion of D- fructose 6-phosphate and D-mannitol 1-phosphate in the mannitol metabolic pathway. Has a strong preference for NADH over NADPH.

BIOCLASS

Short-chain dehydrogenases reductase

ECNUMBER

EC 1.1.1.17

SEQUENCE

MGKKAIQFGGGNIGRGFVAEFLHEAGYEVVFIDVVDKIIDALKSTPSYEVTEVSEEGEKTKTITNYRAINSKTNEEDVVKEIGTADVVTCAVGPNVLKFIAPVIAKGIDARTASKPVAVIACENAIGATDTLRGFIEQNTDKDRLSSMSERARFANSAIDRIVPNQPPNAGLNVRIEKFYEWTVEQTPFGEFGHPDIPAIHWVDDLKPYIERKLFTVNTGHATTAYYGHMRGKKMIADALADAEIRQIVHKVLEQTAKLITTKHEITEQEQNEYVDTIVKRMSNPFLEDNVERVGRAPLRKLSRNERFIGPASQLAEKGLPFDALLGSIEMALRFQNVPGDEESAELAKILKEMSAEEATGKLTGLEKHHPLYEPVQNVIAKVQKDSK

DRUGINFO

D0P7EK

Mannitol

Approved

目标的 KEGG 通路数据

标题	内容

目标的 Wiki 路径数据

标题	内容

目标的蛋白质ID

标题	内容
TARGETID	T93955
UNIPROID	MTLD_ASPFU
TARGNAME	Aspergillus Mannitol-1-phosphate 5-dehydrogenase (Asperg mpdA)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Aspergillus Mannitol-1-phosphate 5-dehydrogenase (Asperg mpdA)	MGKKAIQFGGGNIGRGFVAEFLHEAGYEVVFIDVVDKIIDALKSTPSYEVTEVSEEGEKTKTITNYRAINSKTNEEDVVKEIGTADVVTCAVGPNVLKFIAPVIAKGIDARTASKPVAVIACENAIGATDTLRGFIEQNTDKDRLSSMSERARFANSAIDRIVPNQPPNAGLNVRIEKFYEWTVEQTPFGEFGHPDIPAIHWVDDLKPYIERKLFTVNTGHATTAYYGHMRGKKMIADALADAEIRQIVHKVLEQTAKLITTKHEITEQEQNEYVDTIVKRMSNPFLEDNVERVGRAPLRKLSRNERFIGPASQLAEKGLPFDALLGSIEMALRFQNVPGDEESAELAKILKEMSAEEATGKLTGLEKHHPLYEPVQNVIAKVQKDSK

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