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靶点信息28(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Sodium/hydrogen exchanger 3 (SLC9A3)
SYNONYMS
SLC9A3; Na(+)/H(+) exchanger 3; NHE-3
FUNCTION
Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
BIOCLASS
Monovalent cation:proton antiporter
SEQUENCE
MWGLGARGPDRGLLLALALGGLARAGGVEVEPGGAHGESGGFQVVTFEWAHVQDPYVIALWILVASLAKIGFHLSHKVTSVVPESALLIVLGLVLGGIVWAADHIASFTLTPTVFFFYLLPPIVLDAGYFMPNRLFFGNLGTILLYAVVGTVWNAATTGLSLYGVFLSGLMGDLQIGLLDFLLFGSLMAAVDPVAVLAVFEEVHVNEVLFIIVFGESLLNDAVTVVLYNVFESFVALGGDNVTGVDCVKGIVSFFVVSLGGTLVGVVFAFLLSLVTRFTKHVRIIEPGFVFIISYLSYLTSEMLSLSAILAITFCGICCQKYVKANISEQSATTVRYTMKMLASSAETIIFMFLGISAVNPFIWTWNTAFVLLTLVFISVYRAIGVVLQTWLLNRYRMVQLEPIDQVVLSYGGLRGAVAFALVVLLDGDKVKEKNLFVSTTIIVVFFTVIFQGLTIKPLVQWLKVKRSEHREPRLNEKLHGRAFDHILSAIEDISGQIGHNYLRDKWSHFDRKFLSRVLMRRSAQKSRDRILNVFHELNLKDAISYVAEGERRGSLAFIRSPSTDNVVNVDFTPRSSTVEASVSYLLRENVSAVCLDMQSLEQRRRSIRDAEDMVTHHTLQQYLYKPRQEYKHLYSRHELTPTEDEKQDREIFHRTMRKRLESFKSTKLGLNQNKKAAKLYKRERAQKRRNSSIPNGKLPMESPAQNFTIKEKDLELSDTEEPPNYDEEMSGGIEFLASVTKDTASDSPAGIDNPVFSPDEALDRSLLARLPPWLSPGETVVPSQRARTQIPYSPGTFCRLMPFRLSSKSVDSFLQADGPEERPPAALPESTHM
DRUGINFO
AZD1772//RDX5791
DRUGINFO
N-(3-Methanesulfonyl-4-methoxy-benzoyl)-guanidine
DRUGINFO
N-(3-Methanesulfonyl-4-methyl-benzoyl)-guanidine
DRUGINFO
N-(4-Bromo-3-methanesulfonyl-benzoyl)-guanidine
DRUGINFO
N-(4-Chloro-3-methanesulfonyl-benzoyl)-guanidine
DRUGINFO
N-(4-Cyano-3-methanesulfonyl-benzoyl)-guanidine
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04964 |
|
| hsa04974 |
|
| hsa04976 |
|
| hsa04978 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Sodium/hydrogen exchanger 3 (SLC9A3) |
|