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靶点信息12(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Regenerating human pro-islet peptide (REG3A)
TARGTYPE
Clinical trial target
SYNONYMS
Regenerating islet-derived protein III-alpha; Regenerating islet-derived protein 3-alpha 15 kDa form; Regenerating islet-derived protein 3-alpha; Reg III-alpha; REG3A; REG-3-alpha; Pancreatitis-associated protein 1; Human proislet peptide; Hepatointestinal pancreatic protein; HIP/PAP
FUNCTION
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway.
PDBSTRUC
4MTH; 2GO0; 1UV0
SEQUENCE
MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKSWTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Regenerating human pro-islet peptide (REG3A) |
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