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靶点信息24(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGTYPE
Clinical trial target
SYNONYMS
PIG15; OK/SW-cl.84; Ferritin heavy chain; Ferritin H subunit; FTHL6; FTH; Cell proliferationinducing gene 15 protein; Cell proliferation-inducing gene 15 protein
FUNCTION
Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Stores iron in a soluble, non-toxic, readily available form.
PDBSTRUC
6IPQ; 6IPP; 6IPO; 6IPC; 6H5I
BIOCLASS
Metal ion oxidoreductase
SEQUENCE
MTTASTSQVRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKHTLGDSDNES
KEGGPATH
hsa04978:Mineral absorption
WIKIPATH
WP1846:Membrane Trafficking
WIKIPATH
WP2007:Iron metabolism in placenta
WIKIPATH
WP2670:Iron uptake and transport
WIKIPATH
WP2784:Binding and Uptake of Ligands by Scavenger Receptors
WIKIPATH
WP2882:Nuclear Receptors Meta-Pathway
WIKIPATH
WP2884:NRF2 pathway
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP2884 |
|
| WP2882 |
|
| WP2784 |
|
| WP2670 |
|
| WP2007 |
|
| WP1846 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
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| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|