靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

REACPATH

R-HSA-1059683:Interleukin-6 signaling

REACPATH

R-HSA-2559582:Senescence-Associated Secretory Phenotype (SASP)

REACPATH

R-HSA-2892247:POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation

REACPATH

R-HSA-452723:Transcriptional regulation of pluripotent stem cells

REACPATH

R-HSA-982772:Growth hormone receptor signaling

INTEPATH

cxcr4_pathway:CXCR4-mediated signaling events

INTEPATH

erbb1_downstream_pathway:ErbB1 downstream signaling

INTEPATH

erbb1_receptor_proximal_pathway:EGF receptor (ErbB1) signaling pathway

INTEPATH

erbb2erbb3pathway:ErbB2/ErbB3 signaling events

INTEPATH

fgf_pathway:FGF signaling pathway

INTEPATH

gmcsf_pathway:GMCSF-mediated signaling events

INTEPATH

hdac_classi_pathway:Signaling events mediated by HDAC Class I

INTEPATH

hes_heypathway:Notch-mediated HES/HEY network

INTEPATH

ifngpathway:IFN-gamma pathway

INTEPATH

il12_2pathway:IL12-mediated signaling events

INTEPATH

il12_stat4pathway:IL12 signaling mediated by STAT4

INTEPATH

il2_1pathway:IL2-mediated signaling events

INTEPATH

il23pathway:IL23-mediated signaling events

INTEPATH

il27pathway:IL27-mediated signaling events

INTEPATH

il6_7pathway:IL6-mediated signaling events

目标的 KEGG 通路数据

标题	内容
hsa04062	Chemokine signaling pathway
hsa04066	HIF-1 signaling pathway
hsa04068	FoxO signaling pathway
hsa04550	Signaling pathways regulating pluripotency of stem cells
hsa04630	Jak-STAT signaling pathway
hsa04917	Prolactin signaling pathway
hsa04920	Adipocytokine signaling pathway
hsa05145	Toxoplasmosis
hsa05160	Hepatitis C
hsa05161	Hepatitis B
hsa05162	Measles
hsa05169	Epstein-Barr virus infection
hsa05200	Pathways in cancer
hsa05203	Viral carcinogenesis
hsa05205	Proteoglycans in cancer
hsa05206	MicroRNAs in cancer
hsa05212	Pancreatic cancer
hsa05221	Acute myeloid leukemia
hsa05321	Inflammatory bowel disease (IBD)

目标的 Wiki 路径数据

标题	内容
WP733	Serotonin Receptor 2 and STAT3 Signaling
WP61	Notch Signaling Pathway
WP585	Interferon type I signaling pathways
WP581	EPO Receptor Signaling
WP560	TGF Beta Signaling Pathway
WP49	IL-2 Signaling Pathway
WP395	IL-4 Signaling Pathway
WP364	IL-6 signaling pathway
WP313	Signaling of Hepatocyte Growth Factor Receptor
WP304	Kit receptor signaling pathway
WP2868	TCA Cycle Nutrient Utilization and Invasiveness of Ovarian Cancer
WP286	IL-3 Signaling Pathway
WP2855	Dopaminergic Neurogenesis
WP2821	Transcriptional regulation of pluripotent stem cells
WP2815	Mammary gland development pathway - Involution (Stage 4 of 4)
WP2713	Signaling by SCF-KIT
WP2704	Interleukin-6 signaling
WP2657	Growth hormone receptor signaling
WP2593	JAK/STAT
WP2526	PDGF Pathway
WP2380	BDNF signaling pathway
WP2374	Oncostatin M Signaling Pathway
WP236	Adipogenesis
WP2332	Interleukin-11 Signaling Pathway
WP2324	AGE/RAGE pathway
WP2263	Prostate Cancer
WP2203	TSLP Signaling Pathway
WP22	IL-9 Signaling Pathway
WP2112	IL17 signaling pathway
WP205	IL-7 Signaling Pathway
WP2038	Regulation of Microtubule Cytoskeleton
WP2034	Leptin signaling pathway
WP2032	TSH signaling pathway
WP2029	Cell Differentiation - Index
WP2023	Cell Differentiation - meta
WP1916	Signaling by PDGF
WP1873	NGF signalling via TRKA from the plasma membrane
WP1559	TFs Regulate miRNAs related to cardiac hypertrophy
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP1528	Physiological and Pathological Hypertrophy of the Heart
WP138	Androgen receptor signaling pathway
WP127	IL-5 Signaling Pathway

目标的蛋白质ID

标题	内容
TARGETID	T86803
UNIPROID	STAT3_HUMAN
TARGNAME	STAT3 messenger RNA (STAT3 mRNA)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
STAT3 messenger RNA (STAT3 mRNA)	MAQWNQLQQLDTRYLEQLHQLYSDSFPMELRQFLAPWIESQDWAYAASKESHATLVFHNLLGEIDQQYSRFLQESNVLYQHNLRRIKQFLQSRYLEKPMEIARIVARCLWEESRLLQTAATAAQQGGQANHPTAAVVTEKQQMLEQHLQDVRKRVQDLEQKMKVVENLQDDFDFNYKTLKSQGDMQDLNGNNQSVTRQKMQQLEQMLTALDQMRRSIVSELAGLLSAMEYVQKTLTDEELADWKRRQQIACIGGPPNICLDRLENWITSLAESQLQTRQQIKKLEELQQKVSYKGDPIVQHRPMLEERIVELFRNLMKSAFVVERQPCMPMHPDRPLVIKTGVQFTTKVRLLVKFPELNYQLKIKVCIDKDSGDVAALRGSRKFNILGTNTKVMNMEESNNGSLSAEFKHLTLREQRCGNGGRANCDASLIVTEELHLITFETEVYHQGLKIDLETHSLPVVVISNICQMPNAWASILWYNMLTNNPKNVNFFTKPPIGTWDQVAEVLSWQFSSTTKRGLSIEQLTTLAEKLLGPGVNYSGCQITWAKFCKENMAGKGFSFWVWLDNIIDLVKKYILALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFTWVEKDISGKTQIQSVEPYTKQQLNNMSFAEIIMGYKIMDATNILVSPLVYLYPDIPKEEAFGKYCRPESQEHPEADPGSAAPYLKTKFICVTPTTCSNTIDLPMSPRTLDSLMQFGNNGEGAEPSAGGQFESLTFDMELTSECATSPM

标题

内容

STAT3 messenger RNA (STAT3 mRNA)

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