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靶点信息49(本栏目收费,不能显示细节,电话13136136841)

靶点信息

标题

内容

相关药物

状态

REACPATH

R-HSA-2219530:Constitutive Signaling by Aberrant PI3K in Cancer

REACPATH

R-HSA-389356:CD28 co-stimulation

REACPATH

R-HSA-389357:CD28 dependent PI3K/Akt signaling

REACPATH

R-HSA-389359:CD28 dependent Vav1 pathway

NET_PATH

NetPath_11:TCR Signaling Pathway

INTEPATH

cd8tcrpathway:TCR signaling in naïve CD8+ T cells

INTEPATH

il12_stat4pathway:IL12 signaling mediated by STAT4

INTEPATH

tcr_pathway:TCR signaling in naïve CD4+ T cells

PANTPATH

P00053:T cell activation

目标的 KEGG 通路数据

标题	内容
hsa04514	Cell adhesion molecules (CAMs)
hsa04660	T cell receptor signaling pathway
hsa04672	Intestinal immune network for IgA production
hsa04940	Type I diabetes mellitus
hsa05162	Measles
hsa05320	Autoimmune thyroid disease
hsa05322	Systemic lupus erythematosus
hsa05323	Rheumatoid arthritis
hsa05330	Allograft rejection
hsa05332	Graft-versus-host disease
hsa05416	Viral myocarditis

目标的 Wiki 路径数据

标题	内容
WP69	TCR Signaling Pathway
WP453	Inflammatory Response Pathway
WP2684	Host Interactions of HIV factors
WP2653	PIP3 activates AKT signaling
WP2583	T-Cell Receptor and Co-stimulatory Signaling
WP2328	Allograft Rejection
WP1799	Costimulation by the CD28 family

目标的蛋白质ID

标题	内容
TARGETID	T85529
UNIPROID	CD28_HUMAN
TARGNAME	T-cell-specific surface glycoprotein CD28 (CD28)
TARGTYPE	Successful target

目标的序列数据

标题	内容
T-cell-specific surface glycoprotein CD28 (CD28)	MLRLLLALNLFPSIQVTGNKILVKQSPMLVAYDNAVNLSCKYSYNLFSREFRASLHKGLDSAVEVCVVYGNYSQQLQVYSKTGFNCDGKLGNESVTFYLQNLYVNQTDIYFCKIEVMYPPPYLDNEKSNGTIIHVKGKHLCPSPLFPGPSKPFWVLVVVGGVLACYSLLVTVAFIIFWVRSKRSRLLHSDYMNMTPRRPGPTRKHYQPYAPPRDFAAYRS

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