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靶点信息175(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Steroid 11-beta-hydroxylase (CYP11B1)
TARGTYPE
Successful target
SYNONYMS
S11BH; P450C11; P-450c11; CYPXIB1; CYP11B1
FUNCTION
Has steroid 11-beta-hydroxylase activity. In addition to this activity, the 18 or 19-hydroxylation of steroids and the aromatization of androstendione to estrone have also been ascribed to cytochrome P450 XIB.
BIOCLASS
Paired donor oxygen oxidoreductase
SEQUENCE
MALRAKAEVCMAVPWLSLQRAQALGTRAARVPRTVLPFEAMPRRPGNRWLRLLQIWREQGYEDLHLEVHQTFQELGPIFRYDLGGAGMVCVMLPEDVEKLQQVDSLHPHRMSLEPWVAYRQHRGHKCGVFLLNGPEWRFNRLRLNPEVLSPNAVQRFLPMVDAVARDFSQALKKKVLQNARGSLTLDVQPSIFHYTIEASNLALFGERLGLVGHSPSSASLNFLHALEVMFKSTVQLMFMPRSLSRWTSPKVWKEHFEAWDCIFQYGDNCIQKIYQELAFSRPQQYTSIVAELLLNAELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQKATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFLYSLGRNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEMLLLLHHVLKHLQVETLTQEDIKMVYSFILRPSMFPLLTFRAIN
DRUGINFO
(3-((1H-imidazol-1-yl)methyl)phenyl)methanol
DRUGINFO
(4-((1H-imidazol-1-yl)methyl)phenyl)methanol
DRUGINFO
1-(2-Phenoxy-ethyl)-1H-imidazole
DRUGINFO
1-(3,4-dihydronaphthalen-2-yl)-1H-imidazole
DRUGINFO
1-(3-Bromobenzyl)-1H-imidazole
目标的 Wiki 路径数据
标题 | 内容 |
WP702 |
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WP43 |
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WP2749 |
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WP2355 |
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目标的蛋白质ID
标题 | 内容 |
TARGETID |
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UNIPROID |
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TARGNAME |
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TARGTYPE |
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目标的序列数据
标题 | 内容 |
Steroid 11-beta-hydroxylase (CYP11B1) |
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