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靶点信息167(本栏目收费,不能显示细节,电话13136136841)

靶点信息

标题

内容

相关药物

状态

INTEPATH

il12_2pathway:IL12-mediated signaling events

INTEPATH

nfkappabalternativepathway:Alternative NF-kappaB pathway

PANTPATH

P00006:Apoptosis signaling pathway

PANTPATH

P00010:B cell activation

PANTPATH

P00031:Inflammation mediated by chemokine and cytokine signaling pathway

PANTPATH

P00053:T cell activation

PANTPATH

P00054:Toll receptor signaling pathway

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04064	NF-kappa B signaling pathway
hsa04380	Osteoclast differentiation
hsa05134	Legionellosis
hsa05166	HTLV-I infection
hsa05169	Epstein-Barr virus infection
hsa05200	Pathways in cancer
hsa05203	Viral carcinogenesis

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP710	DNA Damage Response (only ATM dependent)
WP706	SIDS Susceptibility Pathways
WP2882	Nuclear Receptors Meta-Pathway
WP2794	Cytosolic sensors of pathogen-associated DNA
WP2656	TAK1 activates NFkB by phosphorylation and activation of IKKs complex
WP262	EBV LMP1 signaling
WP231	TNF alpha Signaling Pathway
WP2203	TSLP Signaling Pathway
WP2064	Neural Crest Differentiation
WP2036	TWEAK Signaling Pathway
WP2018	RANKL/RANK Signaling Pathway
WP1904	RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
WP1838	Interleukin-1 processing
WP176	Folate Metabolism
WP1533	Vitamin B12 Metabolism
WP15	Selenium Micronutrient Network
WP1449	Regulation of toll-like receptor signaling pathway

目标的蛋白质ID

标题	内容
TARGETID	T83145
UNIPROID	NFKB1_HUMAN; NFKB2_HUMAN; TF65_HUMAN; RELB_HUMAN; REL_HUMAN
TARGNAME	Nuclear factor NF-kappa-B (NFKB)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Nuclear factor NF-kappa-B (NFKB)	MAEDDPYLGRPEQMFHLDPSLTHTIFNPEVFQPQMALPTDGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQLVTNGKNIHLHAHSLVGKHCEDGICTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTEACIRGYNPGLLVHPDLAYLQAEGGGDRQLGDREKELIRQAALQQTKEMDLSVVRLMFTAFLPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDDIQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDINITKPASVFVQLRRKSDLETSEPKPFLYYPEIKDKEEVQRKRQKLMPNFSDSFGGGSGAGAGGGGMFGSGGGGGGTGSTGPGYSFPHYGFPTYGGITFHPGTTKSNAGMKHGTMDTESKKDPEGCDKSDDKNTVNLFGKVIETTEQDQEPSEATVGNGEVTLTYATGTKEESAGVQDNLFLEKAMQLAKRHANALFDYAVTGDVKMLLAVQRHLTAVQDENGDSVLHLAIIHLHSQLVRDLLEVTSGLISDDIINMRNDLYQTPLHLAVITKQEDVVEDLLRAGADLSLLDRLGNSVLHLAAKEGHDKVLSILLKHKKAALLLDHPNGDGLNAIHLAMMSNSLPCLLLLVAAGADVNAQEQKSGRTALHLAVEHDNISLAGCLLLEGDAHVDSTTYDGTTPLHIAAGRGSTRLAALLKAAGADPLVENFEPLYDLDDSWENAGEDEGVVPGTTPLDMATSWQVFDILNGKPYEPEFTSDDLLAQGDMKQLAEDVKLQLYKLLEIPDPDKNWATLAQKLGLGILNNAFRLSPAPSKTLMDNYEVSGGTVRELVEALRQMGYTEAIEVIQAASSPVKTTSQAHSLPLSPASTRQQIDELRDSDSVCDSGVETSFRKLSFTESLTSGASLLTLNKMPHDYGQEGPLEGKI

标题

内容

Nuclear factor NF-kappa-B (NFKB)

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