靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

WIKIPATH

WP306:Focal Adhesion

WIKIPATH

WP363:Wnt Signaling Pathway Netpath

WIKIPATH

WP399:Wnt Signaling Pathway and Pluripotency

WIKIPATH

WP428:Wnt Signaling Pathway

WIKIPATH

WP560:TGF Beta Signaling Pathway

WIKIPATH

WP706:SIDS Susceptibility Pathways

WIKIPATH

WP710:DNA Damage Response (only ATM dependent)

REACPATH

R-HSA-201681:TCF dependent signaling in response to WNT

REACPATH

R-HSA-201722:Formation of the beta-catenin:TCF transactivating complex

REACPATH

R-HSA-3134973:LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production

REACPATH

R-HSA-375170:CDO in myogenesis

REACPATH

R-HSA-3769402:Deactivation of the beta-catenin transactivating complex

REACPATH

R-HSA-4086398:Ca2+ pathway

REACPATH

R-HSA-4411364:Binding of TCF/LEF:CTNNB1 to target gene promoters

REACPATH

R-HSA-4641262:Disassembly of the destruction complex and recruitment of AXIN to the membrane

REACPATH

R-HSA-5358747:S33 mutants of beta-catenin aren't phosphorylated

REACPATH

R-HSA-5358749:S37 mutants of beta-catenin aren't phosphorylated

REACPATH

R-HSA-5358751:S45 mutants of beta-catenin aren't phosphorylated

REACPATH

R-HSA-5358752:T41 mutants of beta-catenin aren't phosphorylated

REACPATH

R-HSA-5626467:RHO GTPases activate IQGAPs

目标的 KEGG 通路数据

标题	内容
hsa04015	Rap1 signaling pathway
hsa04310	Wnt signaling pathway
hsa04390	Hippo signaling pathway
hsa04510	Focal adhesion
hsa04520	Adherens junction
hsa04530	Tight junction
hsa04550	Signaling pathways regulating pluripotency of stem cells
hsa04670	Leukocyte transendothelial migration
hsa04916	Melanogenesis
hsa04919	Thyroid hormone signaling pathway
hsa05100	Bacterial invasion of epithelial cells
hsa05130	Pathogenic Escherichia coli infection
hsa05166	HTLV-I infection
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer
hsa05210	Colorectal cancer
hsa05213	Endometrial cancer
hsa05215	Prostate cancer
hsa05216	Thyroid cancer
hsa05217	Basal cell carcinoma
hsa05412	Arrhythmogenic right ventricular cardiomyopathy (ARVC)

目标的 Wiki 路径数据

标题	内容
WP2858	Ectoderm Differentiation
WP2853	Endoderm Differentiation
WP2840	Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
WP2839	Hair Follicle Development: Organogenesis (Part 2 of 3)
WP2804	Hair Follicle Development: Induction (Part 1 of 3)
WP2794	Cytosolic sensors of pathogen-associated DNA
WP2572	Primary Focal Segmental Glomerulosclerosis FSGS
WP2380	BDNF signaling pathway
WP2377	Integrated Pancreatic Cancer Pathway
WP2363	Gastric cancer network 2
WP236	Adipogenesis
WP2355	Corticotropin-releasing hormone
WP2272	Pathogenic Escherichia coli infection
WP2118	Arrhythmogenic Right Ventricular Cardiomyopathy
WP2064	Neural Crest Differentiation
WP2036	TWEAK Signaling Pathway
WP2005	miR-targeted genes in muscle cell - TarBase
WP2004	miR-targeted genes in lymphocytes - TarBase
WP2003	miR-targeted genes in leukocytes - TarBase
WP1984	Integrated Breast Cancer Pathway
WP1865	Myogenesis
WP1591	Heart Development
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP138	Androgen receptor signaling pathway
WP710	DNA Damage Response (only ATM dependent)
WP706	SIDS Susceptibility Pathways
WP560	TGF Beta Signaling Pathway
WP428	Wnt Signaling Pathway
WP399	Wnt Signaling Pathway and Pluripotency
WP363	Wnt Signaling Pathway Netpath
WP306	Focal Adhesion
WP2870	Extracellular vesicle-mediated signaling in recipient cells

目标的蛋白质ID

标题	内容
TARGETID	T82795
UNIPROID	CTNB1_HUMAN
TARGNAME	Beta-catenin (CTNNB1)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Beta-catenin (CTNNB1)	MATQADLMELDMAMEPDRKAAVSHWQQQSYLDSGIHSGATTTAPSLSGKGNPEEEDVDTSQVLYEWEQGFSQSFTQEQVADIDGQYAMTRAQRVRAAMFPETLDEGMQIPSTQFDAAHPTNVQRLAEPSQMLKHAVVNLINYQDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSPQMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVKMLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVKFLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSRVLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAATKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVGGIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLPVVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVRAHQDTQRRTSMGGTQQQFVEGVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLYSPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSVELTSSLFRTEPMAWNETADLGLDIGAQGEPLGYRQDDPSYRSFHSGGYGQDALGMDPMMEHEMGGHHPGADYPVDGLPDLGHAQDLMDGLPPGDSNQLAWFDTDL

标题

内容

Beta-catenin (CTNNB1)

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