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靶点信息33(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Phosphodiesterase 1B (PDE1B)
TARGTYPE
Patented-recorded target
SYNONYMS
PDES1B; PDE1B1; CamPDE 1B; Cam-PDE 1B; Calcium/calmodulindependent 3',5'cyclicnucleotide phosphodiesterase 1B; Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; 63 kDa CamPDE; 63 kDa Cam-PDE
FUNCTION
Has a preference for cGMP as a substrate. Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes.
PDBSTRUC
5W6E; 5UP0; 5UOY; 5B25; 4NPW
BIOCLASS
Phosphoric diester hydrolase
SEQUENCE
MELSPRSPPEMLEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNLEYTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKPKFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHALRTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLLRTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSVFRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPKALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQSQIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVSFRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD
DRUGINFO
US10034861, Example 1
DRUGINFO
US10034861, Example 164
DRUGINFO
US10034861, Example 165
DRUGINFO
US10092575, Example 101
DRUGINFO
US10092575, Example 141
DRUGINFO
US10092575, Example 158
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa00230 |
|
| hsa04020 |
|
| hsa05032 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Phosphodiesterase 1B (PDE1B) |
|