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靶点信息15(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Thioredoxin reductase (PRDX5)
TARGTYPE
Successful target
SYNONYMS
Thioredoxin peroxidase PMP20; TPx type VI; SBBI10; PrxV; Prx-V; Peroxisomal antioxidant enzyme; Peroxiredoxin5, mitochondrial; Peroxiredoxin-5, mitochondrial; Peroxiredoxin V; PLP; Liver tissue 2Dpage spot 71B; Liver tissue 2D-page spot 71B; Antioxidant enzyme B166; Alu corepressor 1; AOEB166; ACR1
FUNCTION
Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively.
PDBSTRUC
4MMM; 4K7O; 4K7N; 4K7I; 3MNG
BIOCLASS
Peroxide acceptor oxidoreductase
SEQUENCE
MGLAGVCALRRSAGYILVGGAGGQSAAAAARRYSEGEWASGGVRSFSRAAAAMAPIKVGDAIPAVEVFEGEPGNKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAEALKAKGVQVVACLSVNDAFVTGEWGRAHKAEGKVRLLADPTGAFGKETDLLLDDSLVSIFGNRRLKRFSMVVQDGIVKALNVEPDGTGLTCSLAPNIISQL
DRUGINFO
Motexafin gadolinium
DRUGINFO
Diterpene triepoxide derivative 1
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Thioredoxin reductase (PRDX5) |
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