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靶点信息219(本栏目收费,不能显示细节,电话13136136841)

靶点信息

标题

内容

相关药物

状态

DRUGINFO

PD-0183812

DRUGINFO

(2'Z,3'E)-5-Chloro-5'-chloro-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Chloro-5'-fluoro-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Chloro-5'-hydroxy-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Chloro-5'-methyl-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Fluoro-5'-chloro-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Fluoro-5'-fluoro-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Fluoro-5'-hydroxy-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Fluoro-5'-methoxy-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Fluoro-5'-methyl-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Nitro-5'-chloro-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Nitro-5'-fluoro-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Nitro-5'-hydroxy-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Nitro-5'-methoxy-indirubin-3'-oxime

DRUGINFO

(2'Z,3'E)-5-Nitro-5'-methyl-indirubin-3'-oxime

DRUGINFO

10Z-Hymenialdisine

DRUGINFO

1-Amino-6-Cyclohex-3-Enylmethyloxypurine

DRUGINFO

2-((3,5-diamino-1H-pyrazol-4-yl)diazenyl)phenol

DRUGINFO

2-Amino-6-Chloropyrazine

DRUGINFO

2-ANILINO-6-CYCLOHEXYLMETHOXYPURINE

目标的 KEGG 通路数据

标题	内容
hsa04068	FoxO signaling pathway
hsa04110	Cell cycle
hsa04114	Oocyte meiosis
hsa04115	p53 signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04914	Progesterone-mediated oocyte maturation
hsa05161	Hepatitis B
hsa05162	Measles
hsa05168	Herpes simplex infection
hsa05169	Epstein-Barr virus infection
hsa05200	Pathways in cancer
hsa05203	Viral carcinogenesis
hsa05215	Prostate cancer
hsa05222	Small cell lung cancer

目标的 Wiki 路径数据

标题	内容
WP707	DNA Damage Response
WP53	ID signaling pathway
WP466	DNA Replication
WP45	G1 to S cell cycle control
WP2785	M/G1 Transition
WP2772	S Phase
WP2698	Meiotic Recombination
WP2586	Aryl Hydrocarbon Receptor
WP2516	ATM Signaling Pathway
WP2446	Retinoblastoma (RB) in Cancer
WP2431	Spinal Cord Injury
WP2377	Integrated Pancreatic Cancer Pathway
WP2374	Oncostatin M Signaling Pathway
WP2263	Prostate Cancer
WP2261	Signaling Pathways in Glioblastoma
WP2032	TSH signaling pathway
WP1984	Integrated Breast Cancer Pathway
WP1971	Integrated Cancer pathway
WP1925	Synthesis of DNA
WP1898	Regulation of DNA replication
WP1859	Mitotic G2-G2/M phases
WP1858	Mitotic G1-G1/S phases
WP1815	Factors involved in megakaryocyte development and platelet production
WP179	Cell Cycle
WP1782	APC/C-mediated degradation of cell cycle proteins
WP1775	Cell Cycle Checkpoints
WP1530	miRNA Regulation of DNA Damage Response

目标的蛋白质ID

标题	内容
TARGETID	T70176
UNIPROID	CDK2_HUMAN
TARGNAME	Cyclin-dependent kinase 2 (CDK2)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Cyclin-dependent kinase 2 (CDK2)	MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLRL

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