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靶点信息23(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Orphan nuclear receptor NR1I3 (NR1I3)
TARGTYPE
Successful target
SYNONYMS
Orphan nuclear receptor MB67; Orphan nuclear receptor CAR; Nuclear receptor subfamily 1 group I member 3; Nuclear receptor CAR; Constitutive androstane receptor; Constitutive active response; Constitutive activator of retinoid response; CAR
FUNCTION
Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element. Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes.
BIOCLASS
Nuclear hormone receptor
SEQUENCE
MASREDELRNCVVCGDQATGYHFNALTCEGCKGFFRRTVSKSIGPTCPFAGSCEVSKTQRRHCPACRLQKCLDAGMRKDMILSAEALALRRAKQAQRRAQQTPVQLSKEQEELIRTLLGAHTRHMGTMFEQFVQFRPPAHLFIHHQPLPTLAPVLPLVTHFADINTFMVLQVIKFTKDLPVFRSLPIEDQISLLKGAAVEICHIVLNTTFCLQTQNFLCGPLRYTIEDGARVSPTVGFQVEFLELLFHFHGTLRKLQLQEPEYVLLAAMALFSPDRPGVTQRDEIDQLQEEMALTLQSYIKGQQRRPRDRFLYAKLLGLLAELRSINEAYGYQIQHIQGLSAMMPLLQEICS
DRUGINFO
(5BETA)-PREGNANE-3,20-DIONE
WIKIPATH
WP170:Nuclear Receptors
WIKIPATH
WP2289:Drug Induction of Bile Acid Pathway
WIKIPATH
WP2875:Constitutive Androstane Receptor Pathway
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP299 |
|
| WP2882 |
|
| WP2875 |
|
| WP2289 |
|
| WP170 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Orphan nuclear receptor NR1I3 (NR1I3) |
|