靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

INTEPATH

il6_7pathway:IL6-mediated signaling events

INTEPATH

ilk_pathway:Integrin-linked kinase signaling

INTEPATH

lysophospholipid_pathway:LPA receptor mediated events

INTEPATH

met_pathway:Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

INTEPATH

nephrin_neph1_pathway:Nephrin/Neph1 signaling in the kidney podocyte

INTEPATH

nfat_tfpathway:Calcineurin-regulated NFAT-dependent transcription in lymphocytes

INTEPATH

p38alphabetadownstreampathway:Signaling mediated by p38-alpha and p38-beta

INTEPATH

p53downstreampathway:Direct p53 effectors

INTEPATH

pdgfrapathway:PDGFR-alpha signaling pathway

INTEPATH

pdgfrbpathway:PDGFR-beta signaling pathway

INTEPATH

ps1pathway:Presenilin action in Notch and Wnt signaling

INTEPATH

rac1_pathway:RAC1 signaling pathway

INTEPATH

rb_1pathway:Regulation of retinoblastoma protein

INTEPATH

reg_gr_pathway:Glucocorticoid receptor regulatory network

INTEPATH

ret_pathway:Signaling events regulated by Ret tyrosine kinase

INTEPATH

rhoa_pathway:RhoA signaling pathway

INTEPATH

s1p_s1p2_pathway:S1P2 pathway

INTEPATH

smad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling

INTEPATH

tcrcalciumpathway:Calcium signaling in the CD4+ TCR pathway

INTEPATH

tcrjnkpathway:JNK signaling in the CD4+ TCR pathway

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04024	cAMP signaling pathway
hsa04310	Wnt signaling pathway
hsa04380	Osteoclast differentiation
hsa04510	Focal adhesion
hsa04620	Toll-like receptor signaling pathway
hsa04660	T cell receptor signaling pathway
hsa04662	B cell receptor signaling pathway
hsa04668	TNF signaling pathway
hsa04722	Neurotrophin signaling pathway
hsa04912	GnRH signaling pathway
hsa04915	Estrogen signaling pathway
hsa04921	Oxytocin signaling pathway
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
hsa05030	Cocaine addiction
hsa05031	Amphetamine addiction
hsa05120	Epithelial cell signaling in Helicobacter pylori infection
hsa05132	Salmonella infection
hsa05133	Pertussis
hsa05140	Leishmaniasis
hsa05142	Chagas disease (American trypanosomiasis)
hsa05161	Hepatitis B
hsa05164	Influenza A
hsa05166	HTLV-I infection
hsa05168	Herpes simplex infection
hsa05169	Epstein-Barr virus infection
hsa05200	Pathways in cancer
hsa05203	Viral carcinogenesis
hsa05210	Colorectal cancer
hsa05211	Renal cell carcinoma
hsa05231	Choline metabolism in cancer
hsa05321	Inflammatory bowel disease (IBD)
hsa05323	Rheumatoid arthritis

目标的 Wiki 路径数据

标题	内容
WP75	Toll-like receptor signaling pathway
WP712	Estrogen signaling pathway
WP710	DNA Damage Response (only ATM dependent)
WP706	SIDS Susceptibility Pathways
WP69	TCR Signaling Pathway
WP673	ErbB Signaling Pathway
WP615	Senescence and Autophagy in Cancer
WP560	TGF Beta Signaling Pathway
WP49	IL-2 Signaling Pathway
WP481	Insulin Signaling
WP437	EGF/EGFR Signaling Pathway
WP428	Wnt Signaling Pathway
WP422	MAPK Cascade
WP399	Wnt Signaling Pathway and Pluripotency
WP382	MAPK Signaling Pathway
WP366	TGF beta Signaling Pathway
WP3286	Copper homeostasis
WP314	FAS pathway and Stress induction of HSP regulation
WP313	Signaling of Hepatocyte Growth Factor Receptor
WP306	Focal Adhesion
WP289	Myometrial Relaxation and Contraction Pathways
WP2882	Nuclear Receptors Meta-Pathway
WP2881	Estrogen Receptor Pathway
WP2873	Aryl Hydrocarbon Receptor Pathway
WP286	IL-3 Signaling Pathway
WP2840	Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
WP28	Selenium Metabolism and Selenoproteins
WP2786	Pre-NOTCH Expression and Processing
WP2759	Fc epsilon receptor (FCERI) signaling
WP2571	Polycystic Kidney Disease Pathway
WP254	Apoptosis
WP2526	PDGF Pathway
WP2516	ATM Signaling Pathway
WP2435	Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis
WP2380	BDNF signaling pathway
WP2377	Integrated Pancreatic Cancer Pathway
WP2324	AGE/RAGE pathway
WP231	TNF alpha Signaling Pathway
WP23	B Cell Receptor Signaling Pathway
WP2263	Prostate Cancer
WP2100	Arylhydrocarbon receptor (AhR) signaling pathway
WP2036	TWEAK Signaling Pathway
WP2032	TSH signaling pathway
WP2018	RANKL/RANK Signaling Pathway
WP1984	Integrated Breast Cancer Pathway
WP195	IL-1 signaling pathway
WP1845	MAPK targets/ Nuclear events mediated by MAP kinases
WP1772	Apoptosis Modulation and Signaling
WP1528	Physiological and Pathological Hypertrophy of the Heart
WP1449	Regulation of toll-like receptor signaling pathway
WP138	Androgen receptor signaling pathway
WP127	IL-5 Signaling Pathway

目标的蛋白质ID

标题	内容
TARGETID	T69085
UNIPROID	JUN_HUMAN
TARGNAME	Transcription factor AP-1 (JUN)
TARGTYPE	Discontinued target

目标的序列数据

标题	内容
Transcription factor AP-1 (JUN)	MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDLLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF

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