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靶点信息85(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Cathepsin S (CTSS)
TARGTYPE
Clinical trial target
SYNONYMS
Cysteine protease cathepsin S
FUNCTION
Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L. Thiol protease.
PDBSTRUC
5QCJ; 5QCI; 5QCH; 5QCG; 5QCF
SEQUENCE
MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI
DRUGINFO
Oxotetrahydro-2-H-furo[3.2-b]pyrrol-4(5-H)-yl derivative 1
DRUGINFO
Phenylalanine derivative 1
DRUGINFO
PMID25399719-Compound-17
目标的 KEGG 通路数据
| 标题 | 内容 |
|---|
| hsa04142 |
|
| hsa04145 |
|
| hsa04612 |
|
| hsa05152 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|