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靶点信息28(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
CD70 antigen (CD27-L)
TARGTYPE
Clinical trial target
SYNONYMS
Tumor necrosis factor ligandsuperfamily member 7; Tumor necrosis factor ligand superfamily member 7; TNFSF7; CD27LG; CD27L; CD27 ligand
FUNCTION
Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. Cytokine that binds to CD27.
BIOCLASS
Cytokine: tumor necrosis factor
SEQUENCE
MPEEGSGCSVRRRPYGCVLRAALVPLVAGLVICLVVCIQRFAQAQQQLPLESLGWDVAELQLNHTGPQQDPRLYWQGGPALGRSFLHGPELDKGQLRIHRDGIYMVHIQVTLAICSSTTASRHHPTTLAVGICSPASRSISLLRLSFHQGCTIASQRLTPLARGDTLCTNLTGTLLPSRNTDETFFGVQWVRP
DRUGINFO
4SCAR19 and 4SCAR70
DRUGINFO
Anti-hCD70 CAR transduced PBL
目标的蛋白质ID
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目标的序列数据
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| CD70 antigen (CD27-L) |
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