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靶点信息127(本栏目收费,不能显示细节,电话13136136841)

靶点信息

标题

内容

相关药物

状态

WHIZPATH

PW000565:Gastric Acid Production

REACPATH

R-HSA-390648:Muscarinic acetylcholine receptors

REACPATH

R-HSA-399997:Acetylcholine regulates insulin secretion

REACPATH

R-HSA-416476:G alpha (q) signalling events

PANTPATH

P00003:Alzheimer disease-amyloid secretase pathway

PANTPATH

P00027:Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway

PANTPATH

P00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway

目标的 KEGG 通路数据

标题	内容
hsa04020	Calcium signaling pathway
hsa04080	Neuroactive ligand-receptor interaction
hsa04725	Cholinergic synapse
hsa04810	Regulation of actin cytoskeleton
hsa04911	Insulin secretion
hsa04970	Salivary secretion
hsa04971	Gastric acid secretion
hsa04972	Pancreatic secretion

目标的 Wiki 路径数据

标题	内容
WP58	Monoamine GPCRs
WP536	Calcium Regulation in the Cardiac Cell
WP51	Regulation of Actin Cytoskeleton
WP455	GPCRs, Class A Rhodopsin-like
WP2664	Gastrin-CREB signalling pathway via PKC and MAPK
WP1831	Integration of energy metabolism
WP1825	GPCR ligand binding
WP1824	GPCR downstream signaling
WP117	GPCRs, Other

目标的蛋白质ID

标题	内容
TARGETID	T67684
UNIPROID	ACM3_HUMAN
TARGNAME	Muscarinic acetylcholine receptor M3 (CHRM3)
TARGTYPE	Successful target

目标的序列数据

标题	内容
Muscarinic acetylcholine receptor M3 (CHRM3)	MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPLGGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSMKRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSFPKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKRMSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL

标题

内容

Muscarinic acetylcholine receptor M3 (CHRM3)

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