靶点信息_药药网

靶点信息

标题

内容

相关药物

状态

INTEPATH

lymphangiogenesis_pathway:VEGFR3 signaling in lymphatic endothelium

INTEPATH

lysophospholipid_pathway:LPA receptor mediated events

INTEPATH

met_pathway:Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

INTEPATH

mtor_4pathway:mTOR signaling pathway

INTEPATH

nephrin_neph1_pathway:Nephrin/Neph1 signaling in the kidney podocyte

INTEPATH

p53regulationpathway:p53 pathway

INTEPATH

p75ntrpathway:p75(NTR)-mediated signaling

INTEPATH

pi3kciaktpathway:Class I PI3K signaling events mediated by Akt

INTEPATH

pi3kplctrkpathway:Trk receptor signaling mediated by PI3K and PLC-gamma

INTEPATH

ptp1bpathway:Signaling events mediated by PTP1B

INTEPATH

reelinpathway:Reelin signaling pathway

INTEPATH

reg_gr_pathway:Glucocorticoid receptor regulatory network

INTEPATH

retinoic_acid_pathway:Retinoic acid receptors-mediated signaling

INTEPATH

s1p_s1p3_pathway:S1P3 pathway

INTEPATH

smad2_3nuclearpathway:Regulation of nuclear SMAD2/3 signaling

INTEPATH

tcr_pathway:TCR signaling in naïve CD4+ T cells

INTEPATH

telomerasepathway:Regulation of Telomerase

INTEPATH

txa2pathway:Thromboxane A2 receptor signaling

INTEPATH

vegfr1_2_pathway:Signaling events mediated by VEGFR1 and VEGFR2

INTEPATH

vegfr1_pathway:VEGFR1 specific signals

目标的 KEGG 通路数据

标题	内容
hsa04010	MAPK signaling pathway
hsa04012	ErbB signaling pathway
hsa04014	Ras signaling pathway
hsa04015	Rap1 signaling pathway
hsa04022	cGMP-PKG signaling pathway
hsa04024	cAMP signaling pathway
hsa04062	Chemokine signaling pathway
hsa04066	HIF-1 signaling pathway
hsa04068	FoxO signaling pathway
hsa04071	Sphingolipid signaling pathway
hsa04150	mTOR signaling pathway
hsa04151	PI3K-Akt signaling pathway
hsa04152	AMPK signaling pathway
hsa04210	Apoptosis
hsa04261	Adrenergic signaling in cardiomyocytes
hsa04370	VEGF signaling pathway
hsa04380	Osteoclast differentiation
hsa04510	Focal adhesion
hsa04530	Tight junction
hsa04550	Signaling pathways regulating pluripotency of stem cells
hsa04611	Platelet activation
hsa04620	Toll-like receptor signaling pathway
hsa04630	Jak-STAT signaling pathway
hsa04660	T cell receptor signaling pathway
hsa04662	B cell receptor signaling pathway
hsa04664	Fc epsilon RI signaling pathway
hsa04666	Fc gamma R-mediated phagocytosis
hsa04668	TNF signaling pathway
hsa04722	Neurotrophin signaling pathway
hsa04725	Cholinergic synapse
hsa04728	Dopaminergic synapse
hsa04910	Insulin signaling pathway
hsa04914	Progesterone-mediated oocyte maturation
hsa04915	Estrogen signaling pathway
hsa04917	Prolactin signaling pathway
hsa04919	Thyroid hormone signaling pathway
hsa04920	Adipocytokine signaling pathway
hsa04922	Glucagon signaling pathway
hsa04923	Regulation of lipolysis in adipocytes
hsa04932	Non-alcoholic fatty liver disease (NAFLD)
hsa04973	Carbohydrate digestion and absorption
hsa05142	Chagas disease (American trypanosomiasis)
hsa05145	Toxoplasmosis
hsa05152	Tuberculosis
hsa05160	Hepatitis C
hsa05161	Hepatitis B
hsa05162	Measles
hsa05164	Influenza A
hsa05166	HTLV-I infection
hsa05169	Epstein-Barr virus infection
hsa05200	Pathways in cancer
hsa05205	Proteoglycans in cancer
hsa05210	Colorectal cancer
hsa05211	Renal cell carcinoma
hsa05212	Pancreatic cancer
hsa05213	Endometrial cancer
hsa05214	Glioma
hsa05215	Prostate cancer
hsa05218	Melanoma
hsa05220	Chronic myeloid leukemia
hsa05221	Acute myeloid leukemia
hsa05222	Small cell lung cancer
hsa05223	Non-small cell lung cancer
hsa05230	Central carbon metabolism in cancer
hsa05231	Choline metabolism in cancer

目标的 Wiki 路径数据

标题	内容
WP2870	Extracellular vesicle-mediated signaling in recipient cells
WP2864	Apoptosis-related network due to altered Notch3 in ovarian cancer
WP286	IL-3 Signaling Pathway
WP2795	Cardiac Hypertrophic Response
WP2777	Translocation of GLUT4 to the Plasma Membrane
WP2733	Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
WP2653	PIP3 activates AKT signaling
WP26	Signal Transduction of S1P Receptor
WP2583	T-Cell Receptor and Co-stimulatory Signaling
WP2572	Primary Focal Segmental Glomerulosclerosis FSGS
WP254	Apoptosis
WP244	Alpha 6 Beta 4 signaling pathway
WP2380	BDNF signaling pathway
WP2377	Integrated Pancreatic Cancer Pathway
WP2374	Oncostatin M Signaling Pathway
WP2355	Corticotropin-releasing hormone
WP2332	Interleukin-11 Signaling Pathway
WP2324	AGE/RAGE pathway
WP231	TNF alpha Signaling Pathway
WP23	B Cell Receptor Signaling Pathway
WP2263	Prostate Cancer
WP2261	Signaling Pathways in Glioblastoma
WP2203	TSLP Signaling Pathway
WP2112	IL17 signaling pathway
WP205	IL-7 Signaling Pathway
WP2038	Regulation of Microtubule Cytoskeleton
WP2036	TWEAK Signaling Pathway
WP2035	FSH signaling pathway
WP2034	Leptin signaling pathway
WP2032	TSH signaling pathway
WP2018	RANKL/RANK Signaling Pathway
WP1984	Integrated Breast Cancer Pathway
WP1982	SREBP signalling
WP1971	Integrated Cancer pathway
WP195	IL-1 signaling pathway
WP1850	Metabolism of nitric oxide
WP185	Integrin-mediated Cell Adhesion
WP1559	TFs Regulate miRNAs related to cardiac hypertrophy
WP1544	MicroRNAs in cardiomyocyte hypertrophy
WP1539	Angiogenesis
WP1471	TOR Signaling
WP1449	Regulation of toll-like receptor signaling pathway
WP1403	AMPK Signaling
WP138	Androgen receptor signaling pathway
WP127	IL-5 Signaling Pathway
WP75	Toll-like receptor signaling pathway
WP710	DNA Damage Response (only ATM dependent)
WP69	TCR Signaling Pathway
WP61	Notch Signaling Pathway
WP581	EPO Receptor Signaling
WP49	IL-2 Signaling Pathway
WP481	Insulin Signaling
WP474	Endochondral Ossification
WP437	EGF/EGFR Signaling Pathway
WP395	IL-4 Signaling Pathway
WP366	TGF beta Signaling Pathway
WP364	IL-6 signaling pathway
WP363	Wnt Signaling Pathway Netpath
WP3286	Copper homeostasis

目标的蛋白质ID

标题	内容
TARGETID	T67619
UNIPROID	AKT1_HUMAN
TARGNAME	RAC-alpha serine/threonine-protein kinase (AKT1)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
RAC-alpha serine/threonine-protein kinase (AKT1)	MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA

标题

内容

RAC-alpha serine/threonine-protein kinase (AKT1)

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