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靶点信息16(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Hematopoietic progenitor cell antigen CD34 (CD34)
TARGTYPE
Clinical trial target
FUNCTION
Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells.
SEQUENCE
MLVRRGARAGPRMPRGWTALCLLSLLPSGFMSLDNNGTATPELPTQGTFSNVSTNVSYQETTTPSTLGSTSLHPVSQHGNEATTNITETTVKFTSTSVITSVYGNTNSSVQSQTSVISTVFTTPANVSTPETTLKPSLSPGNVSDLSTTSTSLATSPTKPYTSSSPILSDIKAEIKCSGIREVKLTQGICLEQNKTSSCAEFKKDRGEGLARVLCGEEQADADAGAQVCSLLLAQSEVRPQCLLLVLANRTEISSKLQLMKKHQSDLKKLGILDFTEQDVASHQSYSQKTLIALVTSGALLAVLGITGYFLMNRRSWSPTGERLGEDPYYTENGGGQGYSSGPGTSPEAQGKASVNRGAQENGTGQATSRNGHSARQHVVADTEL
DRUGINFO
CAR-T cells targeting CD34
WIKIPATH
WP2840:Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
WIKIPATH
WP2849:Hematopoietic Stem Cell Differentiation
NET_PATH
NetPath_7:TGF_beta_Receptor Signaling Pathway
INTEPATH
cmyb_pathway:C-MYB transcription factor network
目标的蛋白质ID
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目标的序列数据
| 标题 | 内容 |
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| Hematopoietic progenitor cell antigen CD34 (CD34) |
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