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靶点信息26(本栏目收费,不能显示细节,电话13136136841)
靶点信息
TARGNAME
Complement factor D (CFD)
TARGTYPE
Clinical trial target
SYNONYMS
Properdin factor D; PFD; DF; C3 convertase activator; Adipsin
FUNCTION
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway.
PDBSTRUC
6QMT; 6QMR; 6FUT; 6FUJ; 6FUI
SEQUENCE
MHSWERLAVLVLLGAAACAAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQVLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTIDHDLLLLQLSEKATLGPAVRPLPWQRVDRDVAPGTLCDVAGWGIVNHAGRRPDSLQHVLLPVLDRATCNRRTHHDGAITERLMCAESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVASYAAWIDSVLA
DRUGINFO
example 373 [WO2012093101]
KEGGPATH
hsa04610:Complement and coagulation cascades
KEGGPATH
hsa05150:Staphylococcus aureus infection
WIKIPATH
WP1798:Complement cascade
目标的 Wiki 路径数据
| 标题 | 内容 |
|---|
| WP558 |
|
| WP2806 |
|
| WP236 |
|
| WP1798 |
|
目标的蛋白质ID
| 标题 | 内容 |
|---|
| TARGETID |
|
| UNIPROID |
|
| TARGNAME |
|
| TARGTYPE |
|
目标的序列数据
| 标题 | 内容 |
|---|
| Complement factor D (CFD) |
|