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靶点信息

标题

内容

相关药物

状态

TARGETID

T61033

FORMERID

TTDC00257

UNIPROID

CNTFR_HUMAN

TARGNAME

Ciliary neurotrophic factor receptor alpha (CNTFR)

GENENAME

CNTFR

TARGTYPE

Clinical trial target

SYNONYMS

Ciliary neurotrophic factor receptor subunit alpha; CNTFR-alpha; CNTFR alpha; CNTF receptor subunit alpha

FUNCTION

The alpha subunit provides the receptor specificity. Binds to CNTF.

PDBSTRUC

1UC6

BIOCLASS

Cytokine receptor

SEQUENCE

MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLALAAAAATASSLLI

DRUGINFO

NT-501

DRUGINFO

PegCNTF

KEGGPATH

hsa04060:Cytokine-cytokine receptor interaction

KEGGPATH

hsa04630:Jak-STAT signaling pathway

WIKIPATH

WP236:Adipogenesis

目标的 KEGG 通路数据

标题	内容
hsa04060	Cytokine-cytokine receptor interaction
hsa04630	Jak-STAT signaling pathway

目标的 Wiki 路径数据

标题	内容
WP236	Adipogenesis

目标的蛋白质ID

标题	内容
TARGETID	T61033
UNIPROID	CNTFR_HUMAN
TARGNAME	Ciliary neurotrophic factor receptor alpha (CNTFR)
TARGTYPE	Clinical Trial target

目标的序列数据

标题	内容
Ciliary neurotrophic factor receptor alpha (CNTFR)	MAAPVPWACCAVLAAAAAVVYAQRHSPQEAPHVQYERLGSDVTLPCGTANWDAAVTWRVNGTDLAPDLLNGSQLVLHGLELGHSGLYACFHRDSWHLRHQVLLHVGLPPREPVLSCRSNTYPKGFYCSWHLPTPTYIPNTFNVTVLHGSKIMVCEKDPALKNRCHIRYMHLFSTIKYKVSISVSNALGHNATAITFDEFTIVKPDPPENVVARPVPSNPRRLEVTWQTPSTWPDPESFPLKFFLRYRPLILDQWQHVELSDGTAHTITDAYAGKEYIIQVAAKDNEIGTWSDWSVAAHATPWTEEPRHLTTEAQAAETTTSTTSSLAPPPTTKICDPGELGSGGGPSAPFLVSVPITLALAAAAATASSLLI

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